CRK5_ARATH » Cysteine-rich receptor-like protein kinase 5

CRK5_ARATH » Cysteine-rich receptor-like protein kinase 5
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Topology in Membrane
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CRK5_ARATH » Cysteine-rich receptor-like protein kinase 5 » Cysteine-rich RLK5; Receptor-like protein kinase 6;
Hydrophobic Thickness 37.6 ± 3.2 Å
Tilt Angle 1 ± 0°
ΔGtransfer -24.0 kcal/mol
ΔGfold -22.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 278-304 (278-309)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 35-130, Salt stress response/antifungal

AA: 145-241, Salt stress response/antifungal

AA: 340-612, PDBID: 1UWH, Subunit B, Seq Identity:45%, Protein tyrosine kinase

UniProt annotation for CRK5_ARATH » Cysteine-rich receptor-like protein kinase 5
FUNCTION: Involved in multiple distinct defense responses. May function as a disease resistance (R) protein.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

SUBUNIT: Interacts with CRKIP1 (KAPP), CRKIP2 and CRKIP3, three kinase-associated type 2C proteins.

INDUCTION: By salicylic acid (SA) or by a bacterial pathogen infection. May be regulated by WRKY DNA-binding proteins at the transcriptional level.

UniProt features for CRK5_ARATH » Cysteine-rich receptor-like protein kinase 5
SIGNAL 1 24 Potential.
CHAIN 25 659 Cysteine-rich receptor-like protein kinase 5.
DOMAIN 28 132 Gnk2-homologous 1.
DOMAIN 138 243 Gnk2-homologous 2.
DOMAIN 340 619 Protein kinase.
ACT_SITE 465 465 Proton acceptor (By similarity).
Amino Acid Sequence for CRK5_ARATH » Cysteine-rich receptor-like protein kinase 5
MSAYTSLNFL FLLTFFIGSL RVSAQLQDPT YVGHVCTNRI SRNSIYFSNL QTLLTSLSSN NAYFSLGSHS LTKGQNSDMV FGLYLCKGDL SPESCRECVI FAAKDTRSRC PGGKEFLIQY DECMLGYSDR NIFMDTVTTT TIITWNTQKV TADQSDRFND AVLSLMKKSA EEAANSTSKK FAVKKSDFSS SQSLYASVQC IPDLTSEDCV MCLQQSIKEL YFNKVGGRFL VPSCNSRYEV YPFYKETIEG TVLPPPVSAP PLPLVSTPSF PPGKGKNSTV IIIAIVVPVA ISVLICVAVF SFHASKRAKK TYDTPEEDDI TTAGSLQFDF KVIEAATDKF SMCNKLGQGG FGQVYKGTLP NGVQVAVKRL SKTSGQGEKE FKNEVVVVAK LQHRNLVKLL GFCLEREEKI LVYEFVSNKS LDYFLFDSRM QSQLDWTTRY KIIGGIARGI LYLHQDSRLT IIHRDLKAGN ILLDADMNPK VADFGMARIF EIDQTEAHTR RVVGTYGYMS PEYAMYGQFS MKSDVYSFGV LVLEIISGRK NSSLYQMDAS FGNLVTYTWR LWSDGSPLDL VDSSFRDSYQ RNEIIRCIHI ALLCVQEDTE NRPTMSAIVQ MLTTSSIALA VPQPPGFFFR SNHEQAGPSM DKSSLCSIDA ASITILAPR