CRK12_ARATH » Putative cysteine-rich receptor-like protein kinase 12

CRK12_ARATH » Putative cysteine-rich receptor-like protein kinase 12
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CRK12_ARATH » Putative cysteine-rich receptor-like protein kinase 12 » Cysteine-rich RLK12;
Hydrophobic Thickness 35.6 ± 3.0 Å
Tilt Angle 25 ± 5°
ΔGtransfer -33.3 kcal/mol
ΔGfold -28.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 303-330 (302-334)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 23-122, Salt stress response/antifungal

AA: 138-241, Salt stress response/antifungal

AA: 367-639, PDBID: 2NRU, Subunit B, Seq Identity:46%, Protein tyrosine kinase

UniProt annotation for CRK12_ARATH » Putative cysteine-rich receptor-like protein kinase 12
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.
UniProt features for CRK12_ARATH » Putative cysteine-rich receptor-like protein kinase 12
SIGNAL 1 18 Potential.
CHAIN 19 690 Putative cysteine-rich receptor-like protein kinase 12.
DOMAIN 19 124 Gnk2-homologous 1.
DOMAIN 131 243 Gnk2-homologous 2.
DOMAIN 367 644 Protein kinase.
ACT_SITE 492 492 Proton acceptor (By similarity).
Amino Acid Sequence for CRK12_ARATH » Putative cysteine-rich receptor-like protein kinase 12
MPLLFLWFFL TSTSLVSALQ TLPCINTTYF IPNSTYDTNR RVILSLLPSN VTSHFGFFNG SIGQAPNRVY AVGMCLPGTE EESCIGCLLS ASNTLLETCL TEENALIWIA NRTICMIRYS DTSFVGSFEL EPHREFLSIH GYKTNETEFN TVWSRLTQRM VQEASSSTDA TWSGAKYYTA DVAALPDSQT LYAMMQCTPD LSPAECNLCL TESVVNYQSC CLGRQGGSIV RLSCAFRAEL YPFGGAFTVM TARPLSQPPP SLIKKGEFFA KFMSNSQEPV KMIQNLYVVV LIFYFLDSGK FSTETIAAIV VPIIVVAIIF LVLLVLSRLF ARRRKSYQEI DLDQSGITTL HFQQLDFKTI EVATENFAKT NKLGQGGFGE VYKGTLVNGT EVAVKRLSKT SEQGAQEFKN EVVLVAKLQH RNLVKLLGYC LEPEEKILVY EFVPNKSLDY FLFDPTKQGQ LDWTKRYNII GGITRGILYL HQDSRLTIIH RDLKASNILL DADMIPKIAD FGMARISGID QSVANTKRIA GTFGYMPPEY VIHGQFSMKS DVYSFGVLIL EIICGKKNRS FYQADTKAEN LVTYVWRLWT NGSPLELVDL TISENCQTEE VIRCIHIALL CVQEDPKDRP NLSTIMMMLT NSSLILSVPQ PPGFFVPQNK ERDSFLSSQF TMGCTSQTKN DVTITNLDPR