CRK10_ARATH » Cysteine-rich receptor-like protein kinase 10

CRK10_ARATH » Cysteine-rich receptor-like protein kinase 10
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CRK10_ARATH » Cysteine-rich receptor-like protein kinase 10 » Cysteine-rich RLK10; Receptor-like protein kinase 4;
Hydrophobic Thickness 37.2 ± 3.8 Å
Tilt Angle 1 ± 1°
ΔGtransfer -28.2 kcal/mol
ΔGfold -24.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 284-309 (282-314)
Pathways none
PDB none
OPM none
Complexes none
Interactions

P2C70, Complex: CRK10:P2C70

Domains

AA: 43-140, Salt stress response/antifungal

AA: 156-250, Salt stress response/antifungal

AA: 348-619, PDBID: 3OMV, Subunit A, Seq Identity:46%, Protein tyrosine kinase

UniProt annotation for CRK10_ARATH » Cysteine-rich receptor-like protein kinase 10
CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

SUBUNIT: Interacts with CRKIP1 (KAPP), CRKIP2 and CRKIP3, three kinase-associated type 2C proteins.

INDUCTION: By salicylic acid (SA) or by a bacterial pathogen infection. May be regulated by WRKY DNA-binding proteins at the transcriptional level.

UniProt features for CRK10_ARATH » Cysteine-rich receptor-like protein kinase 10
SIGNAL 1 34 Potential.
CHAIN 35 669 Cysteine-rich receptor-like protein kinase 10.
DOMAIN 38 142 Gnk2-homologous 1.
DOMAIN 148 252 Gnk2-homologous 2.
DOMAIN 348 634 Protein kinase.
ACT_SITE 473 473 Proton acceptor (By similarity).
Amino Acid Sequence for CRK10_ARATH » Cysteine-rich receptor-like protein kinase 10
MRRNTDQESP IMSYYSSFFF LFLFSFLTSF RVSAQDPTYV YHTCQNTANY TSNSTYNNNL KTLLASLSSR NASYSTGFQN ATVGQAPDRV TGLFNCRGDV STEVCRRCVS FAVNDTLTRC PNQKEATLYY DECVLRYSNQ NILSTLITTG GVILVNTRNV TSNQLDLLSD LVLPTLNQAA TVALNSSKKF GTRKNNFTAL QSFYGLVQCT PDLTRQDCSR CLQLVINQIP TDRIGARIIN PSCTSRYEIY AFYTESAVPP PPPPPSISTP PVSAPPRSGK DGNSKVLVIA IVVPIIVAVL LFIAGYCFLT RRARKSYYTP SAFAGDDITT ADSLQLDYRT IQTATDDFVE SNKIGQGGFG EVYKGTLSDG TEVAVKRLSK SSGQGEVEFK NEVVLVAKLQ HRNLVRLLGF CLDGEERVLV YEYVPNKSLD YFLFDPAKKG QLDWTRRYKI IGGVARGILY LHQDSRLTII HRDLKASNIL LDADMNPKIA DFGMARIFGL DQTEENTSRI VGTYGYMSPE YAMHGQYSMK SDVYSFGVLV LEIISGKKNS SFYQTDGAHD LVSYAWGLWS NGRPLELVDP AIVENCQRNE VVRCVHIGLL CVQEDPAERP TLSTIVLMLT SNTVTLPVPR QPGLFFQSRI GKDPLDTDTT SKSLLGSVDD ASITDIHPR