COX11_HUMAN » Cytochrome c oxidase assembly protein COX11, mitochondrial

COX11_HUMAN » Cytochrome c oxidase assembly protein COX11, mitochondrial
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
COX11_HUMAN » Cytochrome c oxidase assembly protein COX11, mitochondrial »
Hydrophobic Thickness 31.6 ± 2.6 Å
Tilt Angle 7 ± 6°
ΔGtransfer -14.1 kcal/mol
ΔGfold -13.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, HMDB
Topology In
TM Segments 92-113 (85-114)
Pathways

Oxidative phosphorylation (KEGG)

PDB none
OPM none
Complexes none
Interactions

COA3, Complex: COX11:COA3

Domains

AA: 113-263, PDBID: 1SO9, Subunit A, Seq Identity:42%, Cytochrome c oxidase assembly protein CtaG/Cox11

UniProt annotation for COX11_HUMAN » Cytochrome c oxidase assembly protein COX11, mitochondrial
FUNCTION: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

SUBUNIT: Interacts with CNNM4/ACDP4.

TISSUE SPECIFICITY: Ubiquitous.

UniProt features for COX11_HUMAN » Cytochrome c oxidase assembly protein COX11, mitochondrial
TRANSIT 1 ? Mitochondrion (Potential).
CHAIN ? 276 Cytochrome c oxidase assembly protein COX11, mitochondrial.
Amino Acid Sequence for COX11_HUMAN » Cytochrome c oxidase assembly protein COX11, mitochondrial
MGGLWRPGWR CVPFCGWRWI HPGSPTRAAE RVEPFLRPEW SGTGGAERGL RWLGTWKRCS LRARHPALQP PRRPKSSNPF TRAQEEERRR QNKTTLTYVA AVAVGMLGAS YAAVPLYRLY CQTTGLGGSA VAGHASDKIE NMVPVKDRII KISFNADVHA SLQWNFRPQQ TEIYVVPGET ALAFYRAKNP TDKPVIGIST YNIVPFEAGQ YFNKIQCFCF EEQRLNPQEE VDMPVFFYID PEFAEDPRMI KVDLITLSYT FFEAKEGHKL PVPGYN