COA2_YEAST » Cytochrome c oxidase assembly protein 2

COA2_YEAST » Cytochrome c oxidase assembly protein 2
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
COA2_YEAST » Cytochrome c oxidase assembly protein 2 »
Hydrophobic Thickness 28.4 ± 1.9 Å
Tilt Angle 1 ± 1°
ΔGtransfer -16.5 kcal/mol
ΔGfold -8.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 12-31 (12-31)
Pathways none
PDB none
OPM none
Complexes none
Interactions

COA1, Complex: COA1:COA2

COX11, Complex: COX11:COA2

COX14, Complex: COX14:COA2

COX5A, Complex: COX5A:COA2

Domains

AA: 1-68, Cytochrome C oxidase assembly factor 2

UniProt annotation for COA2_YEAST » Cytochrome c oxidase assembly protein 2
FUNCTION: Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane. Seems to be involved in the SHY1-mediated step of cytochrome c oxidase maturation. May aid in stabilizing an early COX1 intermediate containing the nuclear subunits COX5A and COX6.
UniProt features for COA2_YEAST » Cytochrome c oxidase assembly protein 2
CHAIN 1 68 Cytochrome c oxidase assembly protein 2.
Amino Acid Sequence for COA2_YEAST » Cytochrome c oxidase assembly protein 2
MRAVTRNKIV NNLYFSTFLI AFASVAIGSV LPCPAHSVDS DSPAVQQHKL QLAHEQELKR KDALSKKI