COA1_YEAST » Cytochrome c oxidase assembly protein 1

COA1_YEAST » Cytochrome c oxidase assembly protein 1
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
COA1_YEAST » Cytochrome c oxidase assembly protein 1 »
Hydrophobic Thickness 29.2 ± 3.2 Å
Tilt Angle 28 ± 1°
ΔGtransfer -17.6 kcal/mol
ΔGfold -14.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 74-95 (67-97)
Pathways none
PDB none
OPM none
Complexes none
Interactions

COA2, Complex: COA1:COA2

COA3, Complex: COA3:COA1, PubMed

COX14, Complex: COX14:COA1, PubMed

COX5A, Complex: ADT1:COX5A:COA1:COX14:CY1:COX1:COX15:COX4:MSS51:QCR1:SHY1:QCR2:COX6, PubMed

CY1, Complex: ADT1:COX5A:COA1:COX14:CY1:COX1:COX15:COX4:MSS51:QCR1:SHY1:QCR2:COX6, PubMed

FCJ1, Complex: COA1:FCJ1, PubMed

Domains

AA: 74-190, Cytochrome oxidase complex assembly protein 1

UniProt annotation for COA1_YEAST » Cytochrome c oxidase assembly protein 1
FUNCTION: Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane. Involved in a step coupling MSS51-dependent cotranslational insertion of COX1 to the addition of its heme A and copper B cofactors.

SUBUNIT: Interacts with COX1, COX14, MSS51 and SHY1.

MISCELLANEOUS: Present with 1680 molecules/cell in log phase SD medium.

UniProt features for COA1_YEAST » Cytochrome c oxidase assembly protein 1
CHAIN 1 197 Cytochrome c oxidase assembly protein 1.
Amino Acid Sequence for COA1_YEAST » Cytochrome c oxidase assembly protein 1
MMLRLVTKGL PKVTPSAAKA VLVRGSLLHS FSTSARFNNS VAEDEAKIVL KDKNRPLRID RELPDPTTER RKRIAGFLLF SVAIGSALSL IFNYEKTESP IISNTLYYIR RSPATKNILG ESIEFDGIIP WVYGELNSVK GRINITFYIK GDKNVTGTVR LVADRNTHDE EFLIHEWSVT AAGQKIDLLA ENTKTPI