CLV2_ARATH » Leucine-rich repeat receptor-like protein CLAVATA2

CLV2_ARATH » Leucine-rich repeat receptor-like protein CLAVATA2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CLV2_ARATH » Leucine-rich repeat receptor-like protein CLAVATA2 » Receptor-like protein 10;AtRLP10;
Hydrophobic Thickness 34.4 ± 3.4 Å
Tilt Angle 0 ± 9°
ΔGtransfer -19.1 kcal/mol
ΔGfold -9.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 686-708 (684-712)
Pathways none
PDB none
OPM none
Complexes none
Interactions

CLV1, Complex: CLV2:CLV1, PubMed

CRN, Complex: CRN:CLV2

Domains

AA: 97-139, PDBID: 3RGX, Subunit A, Seq Identity:41%, Leucine Rich repeats (2 copies)

AA: 412-434, PDBID: 4MN8, Subunit A, Seq Identity:41%, Leucine Rich Repeat

AA: 435-495, PDBID: 3WPB, Subunit A, Seq Identity:30%, Leucine rich repeat

UniProt annotation for CLV2_ARATH » Leucine-rich repeat receptor-like protein CLAVATA2
FUNCTION: Involved in the perception of CLV3 and CLV3-like peptides, that act as extracellular signals regulating meristems maintenance. Involved in controlling the stem cell population size in shoot and root apical meristems, and during organ development. Promotes the formation of CLV1 multimers.

SUBUNIT: Parts of a tetrameric complex made of one CRN dimer and two CLV2 that can interact with CLV3 and CLV1 dimers. Interacts with CRN.

TISSUE SPECIFICITY: Mostly expressed in apices (e.g. shoot apical meristem and flower buds), and, to a lower extent, in flowers, leaves, seedlings and siliques.

UniProt features for CLV2_ARATH » Leucine-rich repeat receptor-like protein CLAVATA2
SIGNAL 1 25 Potential.
CHAIN 26 720 Leucine-rich repeat receptor-like protein CLAVATA2.
REPEAT 74 97 LRR 1.
REPEAT 98 120 LRR 2.
REPEAT 122 145 LRR 3.
REPEAT 146 165 LRR 4.
REPEAT 241 260 LRR 5.
REPEAT 265 287 LRR 6.
REPEAT 289 311 LRR 7.
REPEAT 316 339 LRR 8.
REPEAT 340 363 LRR 9.
REPEAT 364 385 LRR 10.
REPEAT 388 411 LRR 11.
REPEAT 412 435 LRR 12.
REPEAT 436 457 LRR 13.
REPEAT 460 482 LRR 14.
REPEAT 484 505 LRR 15.
REPEAT 549 571 LRR 16.
REPEAT 573 595 LRR 17.
REPEAT 596 619 LRR 18.
REPEAT 620 641 LRR 19.
Amino Acid Sequence for CLV2_ARATH » Leucine-rich repeat receptor-like protein CLAVATA2
MIKIADFTLF FFIFVFSPSL PLAQSQLPDL DPQDKASLLI FRVSIHDLNR SLSTWYGSSC SNWTGLACQN PTGKVLSLTL SGLNLSSQIH PSLCKLSSLQ SLDLSHNNFS GNIPSCFGSL RNLRTLNLSR NRFVGSIPAT FVSLKELREV VLSENRDLGG VVPHWFGNFS MNLERVDFSF CSFVGELPES LLYLKSLKYL NLESNNMTGT LRDFQQPLVV LNLASNQFSG TLPCFYASRP SLSILNIAEN SLVGGLPSCL GSLKELSHLN LSFNGFNYEI SPRLMFSEKL VMLDLSHNGF SGRLPSRISE TTEKLGLVLL DLSHNSFSGD IPLRITELKS LQALRLSHNL LTGDIPARIG NLTYLQVIDL SHNALTGSIP LNIVGCFQLL ALMISNNNLS GEIQPELDAL DSLKILDISN NHISGEIPLT LAGLKSLEIV DISSNNLSGN LNEAITKWSN LKYLSLARNK FSGTLPSWLF KFDKIQMIDY SSNRFSWFIP DDNLNSTRFK DFQTGGGEGF AEPPGKVEIK ISAAVVAKDE LSFSYNLLSM VGIDLSDNLL HGEIPEALFR QKNIEYLNLS YNFLEGQLPR LEKLPRLKAL DLSHNSLSGQ VIGNISAPPG LTLLNLSHNC FSGIITEKEG LGKFPGALAG NPELCVETPG SKCDPANIDA SQEEIYQNEL VEGPISIWIF CLSAFISFDF GVLGIFCSAR ARSYILQTKA