CLM4_HUMAN » CMRF35-like molecule 4

CLM4_HUMAN » CMRF35-like molecule 4
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CLM4_HUMAN » CMRF35-like molecule 4 » CLM-4; CD300 antigen-like family member D;CMRF35-A4;
Hydrophobic Thickness 35.2 ± 3.2 Å
Tilt Angle 19 ± 8°
ΔGtransfer -25.6 kcal/mol
ΔGfold -13.9 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 162-187 (158-189)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 22-125, PDBID: 2NMS, Subunit A, Seq Identity:64%, Immunoglobulin V-set domain

UniProt annotation for CLM4_HUMAN » CMRF35-like molecule 4
SUBUNIT: Forms complexes with the CD300 family members with exception of CD300c.

TISSUE SPECIFICITY: Expression seems restricted to cells of myeloid lineage.

UniProt features for CLM4_HUMAN » CMRF35-like molecule 4
SIGNAL 1 18 Potential.
CHAIN 19 194 CMRF35-like molecule 4.
DOMAIN 19 125 Ig-like V-type.
DISULFID 39 107 By similarity.
Amino Acid Sequence for CLM4_HUMAN » CMRF35-like molecule 4
MWLSPSLLLL ILPGYSIAAK ITGPTTVNGS EQGSLTVQCA YGSGWETYLK WRCQGADWNY CNILVKTNGS EQEVKKNRVS IRDNQKNHVF TVTMENLKRD DADSYWCGTE RPGIDLGVKV QVTINPGTQT AVSEWTTTTA SLAFTAAATQ KTSSPLTRSP LKSTHFLFLF LLELPLLLSM LGTVLWVNRP QRRS