CL17A_HUMAN » C-type lectin domain family 17, member A

CL17A_HUMAN » C-type lectin domain family 17, member A
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CL17A_HUMAN » C-type lectin domain family 17, member A » Prolectin;
Hydrophobic Thickness 36.0 ± 2.2 Å
Tilt Angle 0 ± 0°
ΔGtransfer -30.0 kcal/mol
ΔGfold -19.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 169-193 (164-196)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 271-374, PDBID: 1K9J, Subunit A, Seq Identity:43%, Lectin C-type domain

UniProt annotation for CL17A_HUMAN » C-type lectin domain family 17, member A
FUNCTION: Cell surface receptor which may be involved in carbohydrate-mediated communication between cells in the germinal center. Binds glycans with terminal alpha-linked mannose or fucose residues.

SUBUNIT: Oligomer; disulfide-linked.

TISSUE SPECIFICITY: Expressed on dividing B-cells of germinal centers in various tissues, including lymph nodes, tonsils, stomach, intestine, appendix and spleen.

UniProt features for CL17A_HUMAN » C-type lectin domain family 17, member A
CHAIN 1 378 C-type lectin domain family 17, member A.
DOMAIN 261 373 C-type lectin.
DISULFID 254 265 By similarity.
DISULFID 282 372 By similarity.
DISULFID 350 364 By similarity.
Amino Acid Sequence for CL17A_HUMAN » C-type lectin domain family 17, member A
MHNLYSITGY PDPPGTMEEE EEDDDYENST PPYKDLPPKP GTMEEEEEDD DYENSTPPYK DLPPKPGTME EEEEDDDYEN STPPYKDLPP KPGSSAPPRP PRAAKETEKP PLPCKPRNMT GLDLAAVTCP PPQLAVNLEP SPLQPSLAAT PVPWLNQRSG GPGCCQKRWM VYLCLLVVTS LFLGCLGLTV TLIKYQELME ELRMLSFQQM TWRTNMTGMA GLAGLKHDIA RVRADTNQSL VELWGLLDCR RITCPEGWLP FEGKCYYFSP STKSWDEARM FCQENYSHLV IINSFAEHLL GARGTQ