CKAP4_HUMAN » Cytoskeleton-associated protein 4

CKAP4_HUMAN » Cytoskeleton-associated protein 4
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
CKAP4_HUMAN » Cytoskeleton-associated protein 4 » 63-kDa cytoskeleton-linking membrane protein;Climp-63; p63;
Hydrophobic Thickness 32.0 ± 3.8 Å
Tilt Angle 0 ± 0°
ΔGtransfer -29.6 kcal/mol
ΔGfold -12.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 107-131 (106-133)
Pathways

Protein processing in endoplasmic reticulum (KEGG)

PDB none
OPM none
Complexes none
Interactions

EGFR, Complex: CKAP4:EGFR, PubMed

Domains none
UniProt annotation for CKAP4_HUMAN » Cytoskeleton-associated protein 4
FUNCTION: High-affinity epithelial cell surface receptor for APF.

FUNCTION: Mediates the anchoring of the endoplasmic reticulum to microtubules.

UniProt features for CKAP4_HUMAN » Cytoskeleton-associated protein 4
CHAIN 1 602 Cytoskeleton-associated protein 4.
COILED 130 214 Potential.
COILED 256 460 Potential.
COILED 533 602 Potential.
Amino Acid Sequence for CKAP4_HUMAN » Cytoskeleton-associated protein 4
MPSAKQRGSK GGHGAASPSE KGAHPSGGAD DVAKKPPPAP QQPPPPPAPH PQQHPQQHPQ NQAHGKGGHR GGGGGGGKSS SSSSASAAAA AAAASSSASC SRRLGRALNF LFYLALVAAA AFSGWCVHHV LEEVQQVRRS HQDFSRQREE LGQGLQGVEQ KVQSLQATFG TFESILRSSQ HKQDLTEKAV KQGESEVSRI SEVLQKLQNE ILKDLSDGIH VVKDARERDF TSLENTVEER LTELTKSIND NIAIFTEVQK RSQKEINDMK AKVASLEESE GNKQDLKALK EAVKEIQTSA KSREWDMEAL RSTLQTMESD IYTEVRELVS LKQEQQAFKE AADTERLALQ ALTEKLLRSE ESVSRLPEEI RRLEEELRQL KSDSHGPKED GGFRHSEAFE ALQQKSQGLD SRLQHVEDGV LSMQVASARQ TESLESLLSK SQEHEQRLAA LQGRLEGLGS SEADQDGLAS TVRSLGETQL VLYGDVEELK RSVGELPSTV ESLQKVQEQV HTLLSQDQAQ AARLPPQDFL DRLSSLDNLK ASVSQVEADL KMLRTAVDSL VAYSVKIETN ENNLESAKGL LDDLRNDLDR LFVKVEKIHE KV