CEA19_HUMAN » Carcinoembryonic antigen-related cell adhesion molecule 19

CEA19_HUMAN » Carcinoembryonic antigen-related cell adhesion molecule 19
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CEA19_HUMAN » Carcinoembryonic antigen-related cell adhesion molecule 19 » Carcinoembryonic antigen-like 1;
Hydrophobic Thickness 30.4 ± 5.4 Å
Tilt Angle 8 ± 0°
ΔGtransfer -34.5 kcal/mol
ΔGfold -15.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 156-181 (156-184)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 36-141, PDBID: 1L6Z, Subunit A, Seq Identity:26%, Immunoglobulin V-set domain

UniProt annotation for CEA19_HUMAN » Carcinoembryonic antigen-related cell adhesion molecule 19
TISSUE SPECIFICITY: Ubiquitous with highest expression in prostate, uterus, fetal brain, mammary gland, adrenal gland, skeletal muscle, small intestine, and kidney, and lower expression in lung, cerebellum, testis, liver, pancreas, bone marrow and ovary.

INDUCTION: Down-regulated by dexamethasone (in vitro).

UniProt features for CEA19_HUMAN » Carcinoembryonic antigen-related cell adhesion molecule 19
SIGNAL 1 32 Potential.
CHAIN 33 300 Carcinoembryonic antigen-related cell adhesion molecule 19.
Amino Acid Sequence for CEA19_HUMAN » Carcinoembryonic antigen-related cell adhesion molecule 19
MEIPMGTQGC FSKSLLLSAS ILVLWMLQGS QAALYIQKIP EQPQKNQDLL LSVQGVPDTF QDFNWYLGEE TYGGTRLFTY IPGIQRPQRD GSAMGQRDIV GFPNGSMLLR RAQPTDSGTY QVAITINSEW TMKAKTEVQV AEKNKELPST HLPTNAGILA ATIIGSLAAG ALLISCIAYL LVTRNWRGQS HRLPAPRGQG SLSILCSAVS PVPSVTPSTW MATTEKPELG PAHDAGDNNI YEVMPSPVLL VSPISDTRSI NPARPLPTPP HLQAEPENHQ YQQDLLNPDP APYCQLVPTS