CDHR4_HUMAN » Cadherin-related family member 4

CDHR4_HUMAN » Cadherin-related family member 4
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CDHR4_HUMAN » Cadherin-related family member 4 » Cadherin-like protein 29;
Hydrophobic Thickness 34.4 ± 2.0 Å
Tilt Angle 0 ± 4°
ΔGtransfer -48.7 kcal/mol
ΔGfold -16.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, HMDB
Topology Out
TM Segments 686-711 (686-715)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 448-541, PDBID: 4ZPL, Subunit A, Seq Identity:29%, Cadherin domain

UniProt annotation for CDHR4_HUMAN » Cadherin-related family member 4
FUNCTION: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (By similarity).
UniProt features for CDHR4_HUMAN » Cadherin-related family member 4
SIGNAL 1 16 Potential.
CHAIN 17 788 Cadherin-related family member 4.
DOMAIN 237 338 Cadherin 1.
DOMAIN 339 449 Cadherin 2.
DOMAIN 444 554 Cadherin 3.
DOMAIN 551 674 Cadherin 4.
Amino Acid Sequence for CDHR4_HUMAN » Cadherin-related family member 4
MVLLRLLVFL FAPVVSDLCS LPCFINVSES QGPGTVLQFL SFNCSSYTPT PTLELLNVQP PTTFFNPPSL ARWQGTYVGK LTLSSSAQLD ALMVNHYKVQ LKFTCGNHVM EGSLSVDVQR DLSHIQCAGQ FASPAGEMIQ VPETVTPGAR LYTLLLPGLE LHGAQMSIIS AQDLPHFPGP FSINEQGWLQ APSQGLLGQA QKVFQLQISV SFGQRQSCQG MVIVKVLPVP SSQVSFLEQA QNITIPENLA PGSEVVQVQA RGVDLRYEIL SPVPSPLFSI GRADGVVRTT TPLELARTSG TAVSRLQVKA FEQGQLWASA KLNLTMNVQL VNLWPPRCLP ALLVSQIPET APVGTVLNTL TCEDPDSVGA TLDYKLWFRS SSNPASLCLY DRVLEVNATL DCDTPGACFQ HAASILVLDG GQPQMTTEVP VLVMVTPINE FSPACAPRTF RVQEDAAPHT LLGSVVGTDM DYPHDNIEYY TSGGPTTFAV DRLSGEVHLL GPLDYEQQRL YRLTVLVIDH GQDQNPNHHL SGSCTITIEV EDVNDHAPEC EPPFQELTIY APLGRSVEVT KMSCQIPQEP QRLIYSYSIV GGNSQNRFIL QGAILVHSDL VLGPFWPEQP RTYELLICVA DAGPSTPHLS TTATIIVHLV PRRASTVATS THRTTVPSTM TPMLVTDTEA FWQPQPWFVV VLTATGALLL LALGWLLGRL LQGLAQLLQA PSKPAQALLL NSIQGTEGSI EGFLEAPKME MSQAPSSVMS LHFDGRAQDS RTGRDYLFNT HTGARRWL