CD83_HUMAN » CD83 antigen

CD83_HUMAN » CD83 antigen
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CD83_HUMAN » CD83 antigen » hCD83; B-cell activation protein;Cell surface protein HB15;
Hydrophobic Thickness 34.4 ± 3.8 Å
Tilt Angle 25 ± 5°
ΔGtransfer -28.1 kcal/mol
ΔGfold -24.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 141-165 (135-169)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 19-127, PDBID: 1A64, Subunit B, Seq Identity:23%, Immunoglobulin V-set domain

UniProt annotation for CD83_HUMAN » CD83 antigen
FUNCTION: May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.

SUBUNIT: Monomer.

TISSUE SPECIFICITY: Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.

UniProt features for CD83_HUMAN » CD83 antigen
SIGNAL 1 19
CHAIN 20 205 CD83 antigen.
DOMAIN 20 114 Ig-like V-type.
DISULFID 35 107 Potential.
Amino Acid Sequence for CD83_HUMAN » CD83 antigen
MSRGLQLLLL SCAYSLAPAT PEVKVACSED VDLPCTAPWD PQVPYTVSWV KLLEGGEERM ETPQEDHLRG QHYHQKGQNG SFDAPNERPY SLKIRNTTSC NSGTYRCTLQ DPDGQRNLSG KVILRVTGCP AQRKEETFKK YRAEIVLLLA LVIFYLTLII FTCKFARLQS IFPDFSKAGM ERAFLPVTSP NKHLGLVTPH KTELV