CD7_HUMAN » T-cell antigen CD7

CD7_HUMAN » T-cell antigen CD7
Magnify CD7_HUMAN » T-cell antigen CD7Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
CD7_HUMAN » T-cell antigen CD7 » GP40;T-cell leukemia antigen;T-cell surface antigen Leu-9;TP41;
Hydrophobic Thickness 31.2 ± 1.8 Å
Tilt Angle 7 ± 4°
ΔGtransfer -35.2 kcal/mol
ΔGfold -16.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 178-203 (178-208)
Pathways

Hematopoietic cell lineage (KEGG)

PDB none
OPM none
Complexes none
Interactions

SCTM1, Complex: SCTM1:CD7, PubMed

Domains

AA: 31-132, PDBID: 1F6L, Subunit L, Seq Identity:35%, Immunoglobulin V-set domain

UniProt annotation for CD7_HUMAN » T-cell antigen CD7
SUBUNIT: Interacts with SECTM1.
UniProt features for CD7_HUMAN » T-cell antigen CD7
SIGNAL 1 25
CHAIN 26 240 T-cell antigen CD7.
DOMAIN 26 130 Ig-like.
REPEAT 145 153 1.
REPEAT 154 162 2.
REPEAT 163 171 3.
REPEAT 172 180 4.
REGION 145 180 4 X 9 AA tandem repeats, potential spacer function.
DISULFID 35 142 Potential.
DISULFID 48 114 Potential.
Amino Acid Sequence for CD7_HUMAN » T-cell antigen CD7
MAGPPRLLLL PLLLALARGL PGALAAQEVQ QSPHCTTVPV GASVNITCST SGGLRGIYLR QLGPQPQDII YYEDGVVPTT DRRFRGRIDF SGSQDNLTIT MHRLQLSDTG TYTCQAITEV NVYGSGTLVL VTEEQSQGWH RCSDAPPRAS ALPAPPTGSA LPDPQTASAL PDPPAASALP AALAVISFLL GLGLGVACVL ARTQIKKLCS WRDKNSAACV VYEDMSHSRC NTLSSPNQYQ