CCME_ECOLI » Cytochrome c-type biogenesis protein CcmE

CCME_ECOLI » Cytochrome c-type biogenesis protein CcmE
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Topology in Bacterial Gram-negative inner membrane
Topologyextracellular side
cytoplasmic side
CCME_ECOLI » Cytochrome c-type biogenesis protein CcmE » Cytochrome c maturation protein E;Heme chaperone CcmE;
Hydrophobic Thickness 33.2 ± 1.8 Å
Tilt Angle 0 ± 4°
ΔGtransfer -20.5 kcal/mol
ΔGfold -17.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 9-30 (3-32)
Pathways none
PDB 1sr3 (30-159)
OPM 1sr3
Complexes none
Interactions

CCMD, Complex: CCME:CCMD, PubMed

Domains

AA: 4-137, PDBID: 1SR3, Subunit A, Seq Identity:100%, CcmE

UniProt annotation for CCME_ECOLI » Cytochrome c-type biogenesis protein CcmE
FUNCTION: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

SUBUNIT: Forms a ternary complex with CcmC and CcmD. Interacts with CcmF. Shuttles between CcmC and CcmF for heme delivery.

UniProt features for CCME_ECOLI » Cytochrome c-type biogenesis protein CcmE
CHAIN 1 159 Cytochrome c-type biogenesis protein CcmE.
Amino Acid Sequence for CCME_ECOLI » Cytochrome c-type biogenesis protein CcmE
MNIRRKNRLW IACAVLAGLA LTIGLVLYAL RSNIDLFYTP GEILYGKRET QQMPEVGQRL RVGGMVMPGS VQRDPNSLKV TFTIYDAEGS VDVSYEGILP DLFREGQGVV VQGELEKGNH ILAKEVLAKH DENYTPPEVE KAMEANHRRP ASVYKDPAS