CASP_HUMAN » Protein CASP

CASP_HUMAN » Protein CASP
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Topology in Golgi apparatus membrane
TopologyGolgi lumenal side
cytoplasmic side
CASP_HUMAN » Protein CASP »
Hydrophobic Thickness 28.0 ± 2.4 Å
Tilt Angle 4 ± 0°
ΔGtransfer -32.8 kcal/mol
ΔGfold -16.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 619-640 (614-647)
Pathways none
PDB none
OPM none
Complexes none
Interactions

CAH12, Complex: CAH12:CASP.CUX1, PubMed

GOGA5, Complex: CASP.CUX1:GOGA5, PubMed

SDC3, Complex: CASP.CUX1:SDC3, PubMed

Domains

AA: 422-643, CASP C terminal

UniProt annotation for CASP_HUMAN » Protein CASP
FUNCTION: May be involved in intra-Golgi retrograde transport.

SUBUNIT: Homodimer; disulfide-linked. Interacts with GOLGA5.

UniProt features for CASP_HUMAN » Protein CASP
CHAIN 1 678 Protein CASP.
COILED 67 450 Potential.
COILED 502 556 Potential.
Amino Acid Sequence for CASP_HUMAN » Protein CASP
MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR EFKKNTPEDL RKQVAPLLKS FQGEIDALSK RSKEAEAAFL NVYKRLIDVP DPVPALDLGQ QLQLKVQRLH DIETENQKLR ETLEEYNKEF AEVKNQEVTI KALKEKIREY EQTLKNQAET IALEKEQKLQ NDFAEKERKL QETQMSTTSK LEEAEHKVQS LQTALEKTRT ELFDLKTKYD EETTAKADEI EMIMTDLERA NQRAEVAQRE AETLREQLSS ANHSLQLASQ IQKAPDVEQA IEVLTRSSLE VELAAKEREI AQLVEDVQRL QASLTKLREN SASQISQLEQ QLSAKNSTLK QLEEKLKGQA DYEEVKKELN ILKSMEFAPS EGAGTQDAAK PLEVLLLEKN RSLQSENAAL RISNSDLSGR CAELQVRITE AVATATEQRE LIARLEQDLS IIQSIQRPDA EGAAEHRLEK IPEPIKEATA LFYGPAAPAS GALPEGQVDS LLSIISSQRE RFRARNQELE AENRLAQHTL QALQSELDSL RADNIKLFEK IKFLQSYPGR GSGSDDTELR YSSQYEERLD PFSSFSKRER QRKYLSLSPW DKATLSMGRL VLSNKMARTI GFFYTLFLHC LVFLVLYKLA WSESMERDCA TFCAKKFADH LHKFHENDNG AAAGDLWQ