BET1_YEAST » Protein transport protein BET1

BET1_YEAST » Protein transport protein BET1
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
BET1_YEAST » Protein transport protein BET1 » Suppressor of loss of YPT1 protein 12;Protein SLY12;
Hydrophobic Thickness 34.6 ± 2.3 Å
Tilt Angle 1 ± 1°
ΔGtransfer -26.9 kcal/mol
ΔGfold -21.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 119-141 (111-141)
Pathways

SNARE interactions in vesicular transport (KEGG)

PDB 1pcx (B=51-58)
OPM none
Complexes

BET1:SC22B:SC24A:SC23A_HUMAN

Interactions

BOS1, Complex: BET1:BOS1, PubMed

ERP1, Complex: ERP1:BET1, PubMed

GOSR1, Complex: GOSR1:BET1, PubMed

NYV1, Complex: BET1:NYV1, PubMed

SEC22, Complex: SEC22:BET1, PubMed

SED5, Complex: SED5:BET1, PubMed

SFT1, Complex: SED5:SFT1:SEC22:BOS1:YKT6:GOSR1:BET1, PubMed

SNC2, Complex: SNC2:BET1, PubMed

USE1, Complex: BET1:USE1

Domains

AA: 57-119, SNARE domain

UniProt annotation for BET1_YEAST » Protein transport protein BET1
FUNCTION: SNARE required for targeting and fusion of ER-derived transport vesicles with the Golgi complex.

SUBUNIT: Component of a SNARE complex consisting of SED5, BOS1, BET1 and SEC22 or YKT6. Interacts with SEC24.

UniProt features for BET1_YEAST » Protein transport protein BET1
CHAIN 1 142 Protein transport protein BET1.
DOMAIN 52 114 t-SNARE coiled-coil homology.
Amino Acid Sequence for BET1_YEAST » Protein transport protein BET1
MSSRFAGGNA YQRDTGRTQL FGPADGSNSL DDNVSSALGS TDKLDYSQST LASLESQSEE QMGAMGQRIK ALKSLSLKMG DEIRGSNQTI DQLGDTFHNT SVKLKRTFGN MMEMARRSGI SIKTWLIIFF MVGVLFFWVW IT