BET1_HUMAN » BET1 homolog

BET1_HUMAN » BET1 homolog
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
BET1_HUMAN » BET1 homolog » hBET1; Golgi vesicular membrane-trafficking protein p18;
Hydrophobic Thickness 30.4 ± 2.6 Å
Tilt Angle 23 ± 8°
ΔGtransfer -24.9 kcal/mol
ΔGfold -19.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 94-117 (92-117)
Pathways

SNARE interactions in vesicular transport (KEGG)

PDB 3egx (D=24-32)
OPM none
Complexes

BET1:SC22B:SC24A:SC23A_HUMAN

Interactions

B2L13, Complex: BET1:B2L13

FMO1, Complex: BET1:FMO1:STX5:GOSR2:GOSR1:SASH3:SC22B, PubMed

GOSR1, Complex: GOSR1:BET1, PubMed

KASH5, Complex: BET1:KASH5

SC22B, Complex: BET1:SC22B:SC23A:SC24A, PDBID: 3egx

STX4, Complex: STX4:BET1

STX5, Complex: BET1:STX5, PubMed

Domains

AA: 31-93, SNARE domain

UniProt annotation for BET1_HUMAN » BET1 homolog
FUNCTION: Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER-derived vesicles with the cis-Golgi membrane (By similarity).

SUBUNIT: Interacts with STX17.

UniProt features for BET1_HUMAN » BET1 homolog
CHAIN 1 118 BET1 homolog.
DOMAIN 26 88 t-SNARE coiled-coil homology.
Amino Acid Sequence for BET1_HUMAN » BET1 homolog
MRRAGLGEGV PPGNYGNYGY ANSGYSACEE ENERLTESLR SKVTAIKSLS IEIGHEVKTQ NKLLAEMDSQ FDSTTGFLGK TMGKLKILSR GSQTKLLCYM MLFSLFVFFI IYWIIKLR