ATD3B_HUMAN » ATPase family AAA domain-containing protein 3B

ATD3B_HUMAN » ATPase family AAA domain-containing protein 3B
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
ATD3B_HUMAN » ATPase family AAA domain-containing protein 3B » AAA-TOB3;
Hydrophobic Thickness 22.8 ± 2.0 Å
Tilt Angle 1 ± 0°
ΔGtransfer -24.3 kcal/mol
ΔGfold -8.9 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 245-263 (243-269)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 27-286, Domain of unknown function (DUF3523)

AA: 348-475, PDBID: 4CR2, Subunit H, Seq Identity:38%, ATPase family associated with various cellular activities (AAA)

UniProt annotation for ATD3B_HUMAN » ATPase family AAA domain-containing protein 3B
FUNCTION: May play a role in a mitochondrial network organization typical for stem cells, characterized by reduced mitochondrial metabolism, low mtDNA copies and fragmentated mitochondrial network. may act by suppressing ATAD3A function, interfering with ATAD3A interaction with matrix nucleoid complexes.
UniProt features for ATD3B_HUMAN » ATPase family AAA domain-containing protein 3B
CHAIN 2 648 ATPase family AAA domain-containing protein 3B.

COILED 69 214

Amino Acid Sequence for ATD3B_HUMAN » ATPase family AAA domain-containing protein 3B
MSWLFGVNKG PKGEGAGPPP PLPPAQPGAE GGGDRGLGDR PAPKDKWSNF DPTGLERAAK AARELEHSRY AKEALNLAQM QEQTLQLEQQ SKLKEYEAAV EQLKSEQIRA QAEERRKTLS EETRQHQARA QYQDKLARQR YEDQLKQQQL LNEENLRKQE ESVQKQEAMR RATVEREMEL RHKNEMLRVE TEARARAKAE RENADIIREQ IRLKASEHRQ TVLESIRTAG TLFGEGFRAF VTDRDKVTAT VAGLTLLAVG VYSAKNATAV TGRFIEARLG KPSLVRETSR ITVLEALRHP IQVSRRLLSR PQDVLEGVVL SPSLEARVRD IAIATRNTKK NRGLYRHILL YGPPGTGKTL FAKKLALHSG MDYAIMTGGD VAPMGREGVT AMHKLFDWAN TSRRGLLLFM DEADAFLRKR ATEEISKDLR ATLNAFLYHM GQHSNKFMLV LASNLPEQFD CAINSRIDVM VHFDLPQQEE RERLVRLHFD NCVLKPATEG KRRLKLAQFD YGRKCSEVAR LTEGMSGREI AQLAVSWQAT AYASKDGVLT EAMMDACVQD AVQQYRQKMR WLKAEGPGRG VEHPLSGVQG ETLTSWSLAT DPSYPCLAGP CTFRICSWMG TGLCPGPLSP RMSCGGGRPF CPPGHPLL