ALE2_ARATH » Receptor-like serine/threonine-protein kinase ALE2

ALE2_ARATH » Receptor-like serine/threonine-protein kinase ALE2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
ALE2_ARATH » Receptor-like serine/threonine-protein kinase ALE2 » Protein ABNORMAL LEAF SHAPE 2;
Hydrophobic Thickness 34.0 ± 3.6 Å
Tilt Angle 37 ± 0°
ΔGtransfer -29.1 kcal/mol
ΔGfold -23.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 256-284 (256-286)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BET12, Complex: ALE2:BET12

MMGT, Complex: ALE2:MMGT

UBC34, Complex: ALE2:UBC34

Domains

AA: 349-616, PDBID: 2NRU, Subunit B, Seq Identity:40%, Protein tyrosine kinase

UniProt annotation for ALE2_ARATH » Receptor-like serine/threonine-protein kinase ALE2
FUNCTION: Required during the differentiation of the protoderm into shoots epidermis and cuticle.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

UniProt features for ALE2_ARATH » Receptor-like serine/threonine-protein kinase ALE2
SIGNAL 1 19 Potential.
CHAIN 20 744 Receptor-like serine/threonine-protein kinase ALE2.
DOMAIN 349 619 Protein kinase.
ACT_SITE 470 470 Proton acceptor (By similarity).
Amino Acid Sequence for ALE2_ARATH » Receptor-like serine/threonine-protein kinase ALE2
MRNFAMLLLL ILLLHSLASF PICFARLFPM SLPFTRSKAH QMHFFHPYLN PSVAPTPSPA FSPNPSRIPP LRHKGHHRHR RWHLRRNATA VSPSSHDCQQ TCVEPLTSTP FGSPCGCVFP MKVQLLLSVA PFSIFPVTNE LEIEVAAGTY LEQSQVKIMG ASADSENQGK TVVDINLVPL GEKFDNTTAT LIYQRFRHKK VPLNETVFGD YEVTHISYPG IPSSSPNGDV TGDAPGGLPI PINATTFANK SQGIGFRTIA IIALSGFVLI LVLVGAISII VKWKKIGKSS NAVGPALAPS INKRPGAGSM FSSSARSSGS DSLMSSMATC ALSVKTFTLS ELEKATDRFS AKRVLGEGGF GRVYQGSMED GTEVAVKLLT RDNQNRDREF IAEVEMLSRL HHRNLVKLIG ICIEGRTRCL IYELVHNGSV ESHLHEGTLD WDARLKIALG AARGLAYLHE DSNPRVIHRD FKASNVLLED DFTPKVSDFG LAREATEGSQ HISTRVMGTF GYVAPEYAMT GHLLVKSDVY SYGVVLLELL TGRRPVDMSQ PSGEENLVTW ARPLLANREG LEQLVDPALA GTYNFDDMAK VAAIASMCVH QEVSHRPFMG EVVQALKLIY NDADETCGDY CSQKDSSVPD SADFKGDLAP SDSSWWNLTP RLRYGQASSF ITMDYSSGPL EDMENRPHSA SSIPRVGGLI LPNRSGPLRP MRSRRNFFRL RGSMSEHGGP SSSRHLWSGN GDWL