ADCK2_HUMAN » Uncharacterized aarF domain-containing protein kinase 2

ADCK2_HUMAN » Uncharacterized aarF domain-containing protein kinase 2
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
ADCK2_HUMAN » Uncharacterized aarF domain-containing protein kinase 2 »
Hydrophobic Thickness 27.8 ± 3.2 Å
Tilt Angle 49 ± 0°
ΔGtransfer -27.7 kcal/mol
ΔGfold -6.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 105-131 (105-139)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 284-389, PDBID: 4PED, Subunit A, Seq Identity:15%, ABC1 family

UniProt annotation for ADCK2_HUMAN » Uncharacterized aarF domain-containing protein kinase 2
FUNCTION: The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
UniProt features for ADCK2_HUMAN » Uncharacterized aarF domain-containing protein kinase 2
CHAIN 1 626 Uncharacterized aarF domain-containing protein kinase 2.
DOMAIN 200 618 Protein kinase.
ACT_SITE 445 445 Proton acceptor.
Amino Acid Sequence for ADCK2_HUMAN » Uncharacterized aarF domain-containing protein kinase 2
MVAPWRVSVR VCLSHLRCFE LRQGLSLLRP SECPRDARLC WLLLGTLPKV VSLCGDVGEG APDVLSRRRV RCSGAAGAGP AESLPRAGPL GGVFLHLRLW LRAGALLVKF FPLLLLYPLT YLAPSVSTLW LHLLLKATET SGPTYIKLGQ WASTRRDLFS EAFCAQFSKL HVRVTPHPWT HTERFLRQAF GDDWGSILSF ENREPVGSGC VAQVYKAYAN TAFLETDSVQ RLGRASCLPP FSHTGAVGGL RELFGYLGNG RKPPENLADQ SFLERLLLPK ADLVGSNAGV SRAQVPGHQP EATNLISVAV KVLHPGLLAQ VHMDLLLMKI GSRVLGVLPG IKWLSLPEIV EEFEKLMVQQ IDLRYEAQNL EHFQVNFRNV KAVKFPTPLR PFVTREVLVE TYEESVPVSS YQQAGIPVDL KRKIARLGIN MLLKMIFVDN FVHADLHPGN ILVQGANGLS SSQEAQLQQA DICDTLVVAV PSSLCPLRLV LLDAGIVAEL QAPDLRNFRA VFMAVVMGQG QRVAELILHH ARASECRDVE GFKTEMAMLV TQARKNTITL EKLHVSSLLS SVFKLLMTHK VKLESNFASI VFAIMVLEGL GRSLDPKLDI LEAARPFLLT GPVCPP