ACBD5_HUMAN » Acyl-CoA-binding domain-containing protein 5

ACBD5_HUMAN » Acyl-CoA-binding domain-containing protein 5
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Topology in Peroxisome membrane
Topologyperoxisome lumenal side
cytoplasmic side
ACBD5_HUMAN » Acyl-CoA-binding domain-containing protein 5 »
Hydrophobic Thickness 29.4 ± 1.6 Å
Tilt Angle 15 ± 7°
ΔGtransfer -18.4 kcal/mol
ΔGfold -13.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC, HMDB
Topology In
TM Segments 503-524 (503-530)
Pathways none
PDB 3flv (41-136)
OPM 3flv
Complexes none
Interactions none
Domains

AA: 42-126, PDBID: 3FLV, Subunit B, Seq Identity:100%, Acyl CoA binding protein

UniProt annotation for ACBD5_HUMAN » Acyl-CoA-binding domain-containing protein 5
FUNCTION: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
UniProt features for ACBD5_HUMAN » Acyl-CoA-binding domain-containing protein 5
CHAIN 1 534 Acyl-CoA-binding domain-containing protein 5.
DOMAIN 41 130 ACB.
REGION 52 61 Acyl-CoA binding.
REGION 72 76 Acyl-CoA binding.
COILED 190 219 Potential.
COILED 447 476 Potential.
Amino Acid Sequence for ACBD5_HUMAN » Acyl-CoA-binding domain-containing protein 5
MFQFHAGSWE SWCCCCLIPA DRPWDRGQHW QLEMADTRSV HETRFEAAVK VIQSLPKNGS FQPTNEMMLK FYSFYKQATE GPCKLSRPGF WDPIGRYKWD AWSSLGDMTK EEAMIAYVEE MKKIIETMPM TEKVEELLRV IGPFYEIVED KKSGRSSDIT SVRLEKISKC LEDLGNVLTS TPNAKTVNGK AESSDSGAES EEEEAQEEVK GAEQSDNDKK MMKKSADHKN LEVIVTNGYD KDGFVQDIQN DIHASSSLNG RSTEEVKPID ENLGQTGKSA VCIHQDINDD HVEDVTGIQH LTSDSDSEVY CDSMEQFGQE ESLDSFTSNN GPFQYYLGGH SSQPMENSGF REDIQVPPGN GNIGNMQVVA VEGKGEVKHG GEDGRNNSGA PHREKRGGET DEFSNVRRGR GHRMQHLSEG TKGRQVGSGG DGERWGSDRG SRGSLNEQIA LVLMRLQEDM QNVLQRLQKL ETLTALQAKS STSTLQTAPQ PTSQRPSWWP FEMSPGVLTF AIIWPFIAQW LVYLYYQRRR RKLN