Vesicle membrane (92 proteins)

Family Protein Name Protein ID Species Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.01.02.14. Butyrophilin subfamily 2 member A2 BT2A2_HUMAN Homo sapiens Out 264-286 (264-293) 33.2 ± 1.8 3 ± 0 -22.6 -41.6
1.01.23.02. Leucine-rich repeat-containing protein 15 LRC15_HUMAN Homo sapiens Out 536-556 (534-567) 30.8 ± 3.4 0 ± 11 -17.2 -17.6
1.01.39.02. Multiple epidermal growth factor-like domains protein 8 MEGF8_HUMAN Homo sapiens Out 2647-2672 (2641-2674) 35.6 ± 1.2 0 ± 0 -22.2 -46.1
1.02.17.02. Neural proliferation differentiation and control protein 1 NPDC1_HUMAN Homo sapiens Out 181-206 (181-213) 39.2 ± 1.2 0 ± 1 -19.2 -40.4
1.03.01.18. Matrix-remodeling-associated protein 8 MXRA8_HUMAN Homo sapiens Out 338-363 (332-367) 34.0 ± 2.0 0 ± 0 -26.5 -44.2
1.03.32.01. T-cell immunomodulatory protein TIP_HUMAN Homo sapiens Out 565-590 (563-595) 38.8 ± 5.6 7 ± 5 -25.5 -26.9
1.03.39.03. CUB and zona pellucida-like domain-containing protein 1 CUZD1_HUMAN Homo sapiens Out 568-590 (568-597) 28.4 ± 1.6 1 ± 0 -12.4 -36.9
1.04.45.01. Vesicular, overexpressed in cancer, prosurvival protein 1 VOPP1_HUMAN Homo sapiens Out 60-82 (56-86) 34.8 ± 2.9 1 ± 2 -16.5 -21.9
1.04.52.02. Integral membrane protein 2B ITM2B_HUMAN Homo sapiens In 53-75 (47-82) 28.4 ± 0.8 0 ± 2 -16.3 -39.5
1.05.01.01. T-SNARE affecting a late Golgi compartment protein 1 TLG1_YEAST Saccharomyces cerevisiae In 204-224 (202-224) 31.2 ± 2.7 1 ± 0 -19.2 -23.9
1.05.01.01. T-SNARE affecting a late Golgi compartment protein 2 TLG2_YEAST Saccharomyces cerevisiae In 314-335 (308-336) 31.2 ± 4.2 1 ± 9 -20.3 -25.0
1.05.01.01. Syntaxin-12 STX12_HUMAN Homo sapiens In 248-274 (242-275) 34.0 ± 2.8 0 ± 0 -26.7 -49.4
1.05.01.01. Syntaxin-1A STX1A_HUMAN Homo sapiens In 263-284 (257-287) 33.4 ± 2.8 7 ± 5 -13.1 -19.5
1.05.01.01. Syntaxin-6 STX6_HUMAN Homo sapiens In 233-255 (230-255) 34.4 ± 2.4 2 ± 1 -24.6 -29.6
1.05.01.01. Syntaxin-8 STX8_HUMAN Homo sapiens In 213-233 (206-233) 31.2 ± 3.0 5 ± 4 -21.7 -25.7
1.05.01.03. Synaptobrevin-A SYBA_DICDI Dictyostelium discoideum In 66-94 (66-94) 30.8 ± 5.4 39 ± 0 -27.4 -32.8
1.05.01.03. Synaptobrevin-B SYBB_DICDI Dictyostelium discoideum In 75-100 (72-100) 38.0 ± 5.2 10 ± 6 -27.2 -33.4
1.05.01.03. Synaptobrevin homolog 1 SNC1_YEAST Saccharomyces cerevisiae In 90-116 (87-116) 38.8 ± 5.0 6 ± 2 -27.2 -32.9
1.05.01.03. Synaptobrevin homolog 2 SNC2_YEAST Saccharomyces cerevisiae In 89-114 (86-114) 34.0 ± 2.6 24 ± 3 -24.6 -32.8
1.05.01.03. Vesicle-associated membrane protein 1 VAMP1_HUMAN Homo sapiens In 95-117 (91-118) 33.2 ± 1.2 0 ± 1 -19.4 -44.1
1.05.01.03. Vesicle-associated membrane protein 2 VAMP2_HUMAN Homo sapiens In 89-114 (89-115) 30.4 ± 1.8 5 ± 3 -21.4 -42.0
1.05.01.03. Vesicle-associated membrane protein 4 VAMP4_HUMAN Homo sapiens In 115-137 (111-140) 31.2 ± 5.0 27 ± 5 -31.5 -30.3
1.05.01.03. Vesicle-associated membrane protein 7 VAMP7_HUMAN Homo sapiens In 187-205 (187-206) 25.6 ± 2.0 0 ± 4 -14.5 -38.5
1.05.01.03. Vesicle-associated membrane protein 8 VAMP8_HUMAN Homo sapiens In 75-99 (70-99) 32.4 ± 5.8 27 ± 4 -25.9 -31.1
1.05.01.05. Vesicle transport through interaction with t-SNAREs homolog 1A VTI1A_HUMAN Homo sapiens In 192-214 (192-216) 34.0 ± 2.2 9 ± 0 -22.1 -26.9
1.05.01.05. Vesicle transport through interaction with t-SNAREs homolog 1A VTI1A_DICDI Dictyostelium discoideum In 193-216 (193-216) 30.8 ± 3.8 29 ± 23 -21.3 -26.3
1.05.01.05. Vesicle transport v-SNARE 12 VTI12_ARATH Arabidopsis thaliana In 199-220 (198-221) 31.8 ± 2.3 4 ± 2 -22.8 -25.7
1.05.01.05. Vesicle transport through interaction with t-SNAREs homolog 1B VTI1B_HUMAN Homo sapiens In 203-228 (200-229) 32.4 ± 2.8 31 ± 0 -14.9 -22.7
1.05.02.01. Synaptotagmin-5 SYT5_ARATH Arabidopsis thaliana Out 3-25 (3-29) 30.0 ± 1.6 0 ± 0 -16.9 -39.8
1.05.02.01. Synaptotagmin-10 SYT10_HUMAN Homo sapiens Out 52-79 (49-79) 40.4 ± 1.8 0 ± 2 -21.3 -38.8
1.05.02.01. Synaptotagmin-11 SYT11_HUMAN Homo sapiens Out 15-36 (15-46) 34.8 ± 3.4 13 ± 13 -11.8 -16.4
1.05.02.01. Synaptotagmin-12 SYT12_HUMAN Homo sapiens Out 22-44 (19-46) 29.6 ± 4.8 30 ± 16 -13.6 -17.3
1.05.02.01. Synaptotagmin-13 SYT13_HUMAN Homo sapiens Out 5-30 (5-33) 35.2 ± 2.8 2 ± 4 -10.3 -40.2
1.05.02.01. Synaptotagmin-14 SYT14_HUMAN Homo sapiens Out 25-46 (23-48) 30.0 ± 2.0 2 ± 1 -20.6 -46.9
1.05.02.01. Synaptotagmin-1 SYT1_HUMAN Homo sapiens Out 58-82 (58-88) 30.8 ± 3.8 44 ± 0 -20.2 -25.2
1.05.02.01. Synaptotagmin-2 SYT2_HUMAN Homo sapiens Out 62-83 (62-92) 31.6 ± 2.2 0 ± 2 -18.1 -36.4
1.05.02.01. Synaptotagmin-3 SYT3_HUMAN Homo sapiens Out 49-74 (49-76) 30.8 ± 3.0 41 ± 1 -15.2 -21.7
1.05.02.01. Synaptotagmin-4 SYT4_HUMAN Homo sapiens Out 13-37 (13-43) 33.2 ± 3.4 1 ± 0 -16.6 -38.3
1.05.02.01. Synaptotagmin-5 SYT5_HUMAN Homo sapiens Out 30-50 (29-57) 31.6 ± 2.0 4 ± 4 -15.8 -41.2
1.05.02.01. Synaptotagmin-6 SYT6_HUMAN Homo sapiens Out 58-83 (56-83) 36.8 ± 1.4 2 ± 0 -26.2 -49.2
1.05.02.01. Synaptotagmin-7 SYT7_HUMAN Homo sapiens Out 16-40 (15-45) 36.4 ± 2.0 2 ± 2 -12.6 -37.0
1.05.02.01. Synaptotagmin-8 SYT8_HUMAN Homo sapiens Out 49-71 (45-80) 33.8 ± 2.0 1 ± 1 -15.3 -16.7
1.05.02.01. Synaptotagmin-9 SYT9_HUMAN Homo sapiens Out 48-73 (48-75) 39.2 ± 3.2 0 ± 0 -15.8 -41.3
1.05.03.01. Transmembrane emp24 domain-containing protein A TMEDA_DICDI Dictyostelium discoideum Out 173-195 (165-202) 27.2 ± 3.4 1 ± 1 -14.7 -36.5
1.05.03.01. Transmembrane emp24 domain-containing protein B TMEDB_DICDI Dictyostelium discoideum Out 175-197 (169-198) 28.0 ± 3.8 3 ± 0 -9.0 -33.4
1.05.03.01. Transmembrane emp24 domain-containing protein 2 TMED2_HUMAN Homo sapiens Out 169-191 (163-198) 32.0 ± 2.0 1 ± 2 -12.4 -35.9
1.05.03.01. Endosomal protein P24B EMP24_YEAST Saccharomyces cerevisiae Out 173-193 (169-198) 29.2 ± 1.6 0 ± 1 -7.6 -30.4
1.05.10.01. Neuron-specific vesicular protein calcyon CALY_HUMAN Homo sapiens In 85-106 (84-111) 30.8 ± 3.2 7 ± 11 -14.6 -21.9
1.05.11.01. Dysferlin DYSF_HUMAN Homo sapiens In 2045-2067 (2035-2067) 34.2 ± 2.7 12 ± 11 -32.9 -36.5
1.05.11.01. Fer-1-like protein 4 FR1L4_HUMAN Homo sapiens In 1758-1780 (1751-1780) 32.8 ± 2.8 9 ± 6 -24.9 -31.0
1.05.11.01. Fer-1-like protein 5 FR1L5_HUMAN Homo sapiens In 1994-2017 (1989-2018) 32.4 ± 3.8 22 ± 19 -21.4 -27.3
1.05.11.01. Fer-1-like protein 6 FR1L6_HUMAN Homo sapiens In 1821-1845 (1809-1845) 30.8 ± 4.0 33 ± 26 -30.8 -32.7
1.05.11.01. Myoferlin MYOF_HUMAN Homo sapiens In 2024-2046 (2016-2048) 31.2 ± 5.0 36 ± 4 -30.1 -33.6
1.05.11.01. Otoferlin OTOF_HUMAN Homo sapiens In 1964-1985 (1958-1986) 32.0 ± 4.2 0 ± 18 -29.4 -31.4
1.05.13.01. Vesicle-associated membrane protein-associated protein A VAPA_HUMAN Homo sapiens In 227-247 (227-247) 30.4 ± 1.4 2 ± 1 -15.1 -44.9
1.05.15.01. Transmembrane protein 106A T106A_HUMAN Homo sapiens In 92-115 (89-115) 35.6 ± 1.4 1 ± 0 -17.4 -49.6
1.05.26.01. Syntabulin SYBU_HUMAN Homo sapiens In 606-628 (604-630) 33.4 ± 2.5 3 ± 2 -8.5 -24.5
1.05.30.01. Myosin-binding protein 1 MYOB1_ARATH Arabidopsis thaliana Out 6-34 (3-37) 42.8 ± 2.6 0 ± 0 -10.4 -51.4
1.05.30.01. Myosin-binding protein 2 MYOB2_ARATH Arabidopsis thaliana Out 16-43 (13-46) 42.0 ± 0.4 1 ± 1 -17.0 -57.6
1.05.30.01. Myosin-binding protein 3 MYOB3_ARATH Arabidopsis thaliana Out 17-45 (14-48) 42.8 ± 1.0 0 ± 0 -19.0 -59.3
1.05.30.01. Myosin-binding protein 4 MYOB4_ARATH Arabidopsis thaliana Out 26-46 (21-52) 30.8 ± 4.6 1 ± 15 -18.4 -25.1
1.05.30.01. Myosin-binding protein 5 MYOB5_ARATH Arabidopsis thaliana Out 16-47 (16-48) 24.0 ± 1.4 3 ± 0 -14.7 -24.7
1.05.30.01. Myosin-binding protein 6 MYOB6_ARATH Arabidopsis thaliana Out 35-66 (35-67) 28.0 ± 5.2 0 ± 0 -8.4 -31.5
1.05.30.01. Myosin-binding protein 7 MYOB7_ARATH Arabidopsis thaliana In 455-476 (452-480) 30.8 ± 4.4 18 ± 13 -7.9 -17.3
1.05.30.01. Uncharacterized protein F4JE14_ARATH Arabidopsis thaliana In 329-350 (329-354) 28.8 ± 1.8 29 ± 0 -6.4 -18.5
1.05.30.01. T10O22.23 Q9LM24_ARATH Arabidopsis thaliana Out 36-56 (32-56) 26.0 ± 1.6 0 ± 1 -14.3 -31.4
1.05.30.01. Putative uncharacterized protein T5N23_100 Q9M1S6_ARATH Arabidopsis thaliana In 377-398 (377-402) 28.8 ± 1.8 29 ± 0 -6.4 -18.5
1.05.31.01. Vacuolar-sorting receptor 6 VSR6_ARATH Arabidopsis thaliana Out 564-585 (564-590) 30.2 ± 3.5 27 ± 3 -17.5 -19.7
1.05.31.01. Vacuolar-sorting receptor 3 VSR3_ARATH Arabidopsis thaliana Out 568-590 (564-596) 34.4 ± 3.0 1 ± 1 -21.2 -35.5
1.05.31.01. Vacuolar-sorting receptor 4 VSR4_ARATH Arabidopsis thaliana Out 568-590 (564-596) 34.8 ± 2.4 7 ± 5 -21.0 -33.7
1.05.31.01. Vacuolar-sorting receptor 5 VSR5_ARATH Arabidopsis thaliana Out 564-584 (560-588) 30.8 ± 3.6 17 ± 10 -18.5 -21.3
1.05.31.01. Vacuolar-sorting receptor 2 VSR2_ARATH Arabidopsis thaliana Out 565-588 (565-594) 29.2 ± 2.4 1 ± 0 -19.8 -37.8
1.05.31.01. Vacuolar-sorting receptor 1 VSR1_ARATH Arabidopsis thaliana Out 566-585 (566-592) 28.8 ± 2.6 1 ± 1 -16.5 -18.1
1.05.42.01. Equatorin EQTN_HUMAN Homo sapiens Out 175-204 (175-210) 33.2 ± 4.0 39 ± 0 -29.5 -28.8
1.09.31.02. Dopamine beta-hydroxylase DOPO_HUMAN Homo sapiens In 15-37 (15-41) 34.0 ± 4.8 9 ± 0 -18.2 -21.3
1.09.34.01. Tyrosinase TYRO_HUMAN Homo sapiens Out 471-503 (468-505) 42.8 ± 1.0 0 ± 1 -21.5 -49.4
1.09.34.01. 5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1_HUMAN Homo sapiens Out 475-500 (475-505) 37.6 ± 1.2 3 ± 1 -23.3 -46.5
1.10.01.13. C1GALT1-specific chaperone 1 C1GLC_HUMAN Homo sapiens In 8-28 (4-30) 32.2 ± 1.9 2 ± 0 -9.7 -18.9
1.11.03.01. Aminopeptidase Q AMPQ_HUMAN Homo sapiens In 14-36 (6-37) 42.0 ± 4.2 0 ± 5 -25.9 -38.7
1.11.20.02. Monoacylglycerol lipase ABHD6 ABHD6_HUMAN Homo sapiens In 5-34 (5-38) 31.6 ± 1.0 45 ± 0 -17.4 -29.2
1.11.20.02. Epoxide hydrolase 4 EPHX4_HUMAN Homo sapiens In 19-40 (15-45) 36.8 ± 8.8 7 ± 3 -4.9 -16.5
1.11.20.03. Abhydrolase domain-containing protein 1 ABHD1_HUMAN Homo sapiens In 13-34 (12-35) 28.0 ± 2.0 7 ± 5 -13.0 -33.2
1.11.20.03. Abhydrolase domain-containing protein 2 ABHD2_HUMAN Homo sapiens In 12-33 (11-37) 31.6 ± 3.5 7 ± 17 -6.0 -17.8
1.11.20.03. Abhydrolase domain-containing protein 3 ABHD3_HUMAN Homo sapiens In 27-49 (20-55) 33.6 ± 2.0 10 ± 6 -10.6 -36.3
1.11.20.06. Alpha/beta hydrolase domain-containing protein 14A ABHEA_HUMAN Homo sapiens In 32-52 (29-52) 27.2 ± 1.2 0 ± 0 -13.6 -34.0
1.11.56.01. Retinoic acid receptor responder protein 1 TIG1_HUMAN Homo sapiens In 21-39 (21-41) 27.2 ± 1.6 15 ± 3 -6.2 -17.5
1.14.01.02. E3 ubiquitin-protein ligase RNF149 RN149_HUMAN Homo sapiens Out 200-224 (199-225) 34.8 ± 1.8 2 ± 1 -24.3 -44.6
1.14.01.10. Probable E3 ubiquitin-protein ligase HECTD4 HECD4_HUMAN Homo sapiens Und 282-301 (280-301) 29.6 ± 3.4 2 ± 8 -5.7 -19.4
1.15.03.23. Protein FAM151A F151A_HUMAN Homo sapiens Und 11-36 (9-38) 39.6 ± 5.4 1 ± 1 -20.0 -28.0
1.15.03.34. Protein FAM209A F209A_HUMAN Homo sapiens Out 59-78 (58-81) 28.4 ± 1.6 0 ± 3 -10.4 -17.7
1.15.03.44. Transmembrane protein 52B TM52B_HUMAN Homo sapiens Out 41-63 (37-66) 30.8 ± 1.8 16 ± 7 -20.2 -20.4
1.15.40.01. SAYSvFN domain-containing protein 1 SMDC1_HUMAN Homo sapiens Und 103-132 (101-135) 42.8 ± 0.2 4 ± 4 -15.1 -33.7