Mitochondrial inner membrane (230 proteins)

Family Protein Name Protein ID Species Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.01.03.22. Uncharacterized aarF domain-containing protein kinase 5 ADCK5_HUMAN Homo sapiens In 46-68 (45-77) 28.8 ± 3.9 22 ± 9 -6.8 -18.6
1.01.03.22. Atypical kinase ADCK3, mitochondrial ADCK3_HUMAN Homo sapiens In 214-237 (213-238) 25.2 ± 1.4 1 ± 0 -5.2 -26.7
1.01.03.22. ABC1 family protein YPL109C, mitochondrial YP109_YEAST Saccharomyces cerevisiae In 118-138 (118-146) 28.6 ± 4.2 10 ± 12 -11.2 -22.3
1.01.03.22. Probable serine/threonine-protein kinase abkD ABKD_DICDI Dictyostelium discoideum In 176-194 (174-194) 26.8 ± 2.3 4 ± 1 -9.5 -16.8
1.01.03.22. Probable serine/threonine-protein kinase abkB ABKB_DICDI Dictyostelium discoideum In 166-190 (159-190) 31.0 ± 3.0 33 ± 25 -6.9 -18.6
1.01.03.22. Uncharacterized aarF domain-containing protein kinase 2 ADCK2_HUMAN Homo sapiens In 105-131 (105-139) 27.8 ± 3.2 49 ± 0 -6.0 -27.7
1.01.03.22. AarF domain-containing protein kinase 4 ADCK4_HUMAN Homo sapiens In 92-113 (85-115) 28.4 ± 1.8 2 ± 1 -7.6 -24.1
1.01.03.22. ABC1 family protein MCP2 MCP2_YEAST Saccharomyces cerevisiae In 32-52 (30-60) 29.6 ± 3.5 8 ± 9 -1.9 -13.0
1.04.01.02. DnaJ homolog subfamily C member 15 DJC15_HUMAN Homo sapiens Out 36-56 (31-56) 29.2 ± 3.0 20 ± 2 -10.6 -15.3
1.04.01.02. J domain-containing protein 1 JID1_YEAST Saccharomyces cerevisiae In 207-231 (207-237) 29.8 ± 5.0 45 ± 0 -8.1 -17.1
1.04.01.03. Mitochondrial import inner membrane translocase subunit TIM14 TIM14_YEAST Saccharomyces cerevisiae Out 65-84 (63-88) 27.6 ± 2.6 1 ± 0 -8.3 -30.0
1.04.01.03. Mitochondrial import inner membrane translocase subunit TIM14 TIM14_HUMAN Homo sapiens Out 2-23 (2-27) 27.8 ± 3.3 24 ± 5 -9.9 -13.0
1.04.01.03. Mitochondrial import inner membrane translocase subunit TIM14-1 TI141_ARATH Arabidopsis thaliana Out 2-17 (2-20) 29.4 ± 4.0 7 ± 10 -5.6 -12.6
1.04.01.03. Mitochondrial import inner membrane translocase subunit TIM14-2 TI142_ARATH Arabidopsis thaliana Out 2-17 (1-20) 32.4 ± 3.2 1 ± 17 -7.7 -12.6
1.04.01.03. Mitochondrial import inner membrane translocase subunit TIM14-3 TI143_ARATH Arabidopsis thaliana Out 2-23 (2-30) 29.0 ± 3.6 30 ± 16 -7.0 -11.4
1.04.01.03. Mitochondrial import inner membrane translocase subunit TIM14 TIM14_DICDI Dictyostelium discoideum Out 2-26 (2-30) 27.8 ± 4.4 48 ± 0 -5.1 -11.8
1.04.54.01. Cytochrome c oxidase assembly protein COX14 COX14_HUMAN Homo sapiens In 12-30 (8-44) 27.0 ± 2.6 3 ± 1 -5.4 -14.3
1.04.54.01. Cytochrome c oxidase assembly protein COX14 COX14_YEAST Saccharomyces cerevisiae In 13-37 (12-42) 29.0 ± 1.2 35 ± 3 -6.1 -15.0
1.04.54.02. Cytochrome c oxidase assembly protein 2 COA2_YEAST Saccharomyces cerevisiae In 12-31 (12-31) 28.4 ± 1.9 1 ± 1 -8.4 -16.5
1.04.54.03. Cytochrome c oxidase assembly protein 1 homolog COA1_HUMAN Homo sapiens In 20-40 (17-43) 26.8 ± 3.4 30 ± 0 -8.5 -18.5
1.04.54.03. Expressed protein Q9SK63_ARATH Arabidopsis thaliana In 28-52 (27-55) 28.6 ± 3.0 34 ± 3 -6.8 -20.6
1.04.54.03. Cytochrome c oxidase assembly protein 1 COA1_YEAST Saccharomyces cerevisiae In 74-95 (67-97) 29.2 ± 3.2 28 ± 1 -14.2 -17.6
1.04.54.04. Cytochrome c oxidase assembly protein 3 homolog, mitochondrial COA3_HUMAN Homo sapiens Out 56-78 (51-81) 33.4 ± 3.8 0 ± 3 -12.8 -18.1
1.04.54.04. Cytochrome c oxidase assembly protein 3, mitochondrial COA3_YEAST Saccharomyces cerevisiae Out 27-49 (26-50) 31.6 ± 2.7 8 ± 7 -4.9 -17.4
1.04.54.05. Cytochrome c oxidase assembly protein COX11, mitochondrial COX11_HUMAN Homo sapiens In 92-113 (85-114) 31.6 ± 2.6 7 ± 6 -13.7 -14.1
1.04.54.05. Cytochrome c oxidase assembly protein COX11, mitochondrial COX11_ARATH Arabidopsis thaliana In 93-111 (85-112) 27.0 ± 3.5 11 ± 0 -11.6 -17.1
1.04.54.05. Cytochrome c oxidase assembly protein COX11, mitochondrial COX11_DICDI Dictyostelium discoideum In 130-151 (120-152) 32.2 ± 2.4 4 ± 3 -15.8 -18.2
1.04.54.05. Cytochrome c oxidase assembly protein COX11, mitochondrial COX11_YEAST Saccharomyces cerevisiae In 86-110 (83-113) 29.4 ± 0.6 32 ± 2 -12.9 -23.5
1.04.54.06. Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial COX16_HUMAN Homo sapiens In 15-37 (14-48) 30.2 ± 4.8 12 ± 6 -6.2 -16.6
1.04.54.06. COX16 protein Q54VU6_DICDI Dictyostelium discoideum In 7-29 (5-31) 33.2 ± 3.2 5 ± 3 -9.9 -20.3
1.04.54.06. At4g14145 A0JPW4_ARATH Arabidopsis thaliana In 42-64 (41-68) 30.2 ± 1.5 7 ± 0 -5.1 -17.3
1.04.54.06. Cytochrome c oxidase assembly protein COX16, mitochondrial COX16_YEAST Saccharomyces cerevisiae In 33-55 (33-60) 28.4 ± 4.0 48 ± 2 -12.5 -23.1
1.04.54.07. Protein PET100 homolog, mitochondrial PT100_HUMAN Homo sapiens Out 3-24 (3-27) 30.4 ± 3.1 4 ± 4 -6.7 -19.7
1.04.54.07. Protein PET100, mitochondrial PT100_YEAST Saccharomyces cerevisiae Out 15-35 (13-41) 29.2 ± 2.9 6 ± 5 -7.5 -19.1
1.04.55.01. Prohibitin-1, mitochondrial PHB1_ARATH Arabidopsis thaliana In 14-32 (14-37) 28.0 ± 4.0 10 ± 7 -1.8 -11.7
1.04.55.01. Prohibitin-2, mitochondrial PHB2_ARATH Arabidopsis thaliana In 14-32 (14-37) 28.4 ± 3.8 9 ± 10 -2.0 -12.9
1.04.55.01. Prohibitin-3, mitochondrial PHB3_ARATH Arabidopsis thaliana In 6-31 (3-34) 30.2 ± 4.0 40 ± 6 -4.2 -14.8
1.04.55.01. Prohibitin-4, mitochondrial PHB4_ARATH Arabidopsis thaliana In 6-28 (3-32) 29.0 ± 2.1 32 ± 1 -6.2 -14.4
1.04.55.01. Prohibitin-5, mitochondrial PHB5_ARATH Arabidopsis thaliana In 2-26 (2-26) 28.2 ± 3.0 34 ± 3 -7.0 -15.8
1.04.55.01. Prohibitin-6, mitochondrial PHB6_ARATH Arabidopsis thaliana In 15-33 (15-35) 28.0 ± 4.0 4 ± 2 -3.7 -9.2
1.04.55.01. Prohibitin-7, mitochondrial PHB7_ARATH Arabidopsis thaliana In 13-30 (13-30) 27.2 ± 0.4 10 ± 2 -5.0 -12.1
1.04.55.01. Prohibitin-2 PHB2_DICDI Dictyostelium discoideum In 21-41 (20-42) 30.0 ± 3.2 1 ± 0 -6.4 -16.6
1.04.55.01. Prohibitin-2 PHB2_YEAST Saccharomyces cerevisiae In 37-55 (37-59) 28.2 ± 2.4 23 ± 5 -5.4 -14.5
1.04.56.01. Mitochondrial import inner membrane translocase subunit tim50 TIM50_DICDI Dictyostelium discoideum In 105-126 (102-130) 29.0 ± 3.2 30 ± 0 -10.2 -17.3
1.04.56.01. Mitochondrial import inner membrane translocase subunit TIM50 TIM50_YEAST Saccharomyces cerevisiae In 112-132 (105-133) 27.0 ± 2.4 24 ± 12 -9.9 -11.0
1.04.56.01. Mitochondrial import inner membrane translocase subunit TIM50 TIM50_HUMAN Homo sapiens In 65-86 (60-86) 30.0 ± 2.4 21 ± 0 -7.5 -13.2
1.04.56.01. Mitochondrial import inner membrane translocase subunit TIM50 TIM50_ARATH Arabidopsis thaliana In 83-104 (74-105) 26.8 ± 1.1 32 ± 1 -9.5 -12.6
1.04.57.01. Mitochondrial import inner membrane translocase subunit TIM21 TIM21_YEAST Saccharomyces cerevisiae In 71-96 (71-97) 31.8 ± 4.2 36 ± 26 -15.9 -24.6
1.04.57.01. Mitochondrial import inner membrane translocase subunit Tim21 TIM21_HUMAN Homo sapiens In 108-129 (108-129) 28.0 ± 3.2 26 ± 7 -12.9 -18.0
1.04.57.01. Probable mitochondrial import inner membrane translocase subunit TIM21 TIM21_ARATH Arabidopsis thaliana In 134-152 (131-155) 27.4 ± 2.9 31 ± 1 -8.2 -12.1
1.04.57.01. Uncharacterized protein Q54E00_DICDI Dictyostelium discoideum In 109-134 (109-135) 29.4 ± 3.8 41 ± 5 -10.6 -20.1
1.04.57.02. Mitochondrial intermembrane space import and assembly protein 40 MIA40_YEAST Saccharomyces cerevisiae In 46-64 (43-65) 27.2 ± 2.7 13 ± 3 -7.4 -15.1
1.04.57.03. Mitochondrial import inner membrane translocase subunit TIM54 TIM54_YEAST Saccharomyces cerevisiae In 37-56 (34-61) 27.4 ± 1.6 11 ± 1 -7.3 -16.9
1.04.58.01. Protein SCO1 homolog 1, mitochondrial SCO11_ARATH Arabidopsis thaliana In 124-145 (124-149) 30.6 ± 2.4 13 ± 1 -13.8 -20.7
1.04.58.01. Protein SCO1 homolog 2, mitochondrial SCO12_ARATH Arabidopsis thaliana In 64-85 (60-90) 31.0 ± 3.4 12 ± 9 -10.8 -15.6
1.04.58.01. Protein SCO2, mitochondrial SCO2_YEAST Saccharomyces cerevisiae In 78- 97 (76-101) 26.8 ± 1.3 12 ± 7 -8.0 -15.1
1.04.58.01. Protein SCO1, mitochondrial SCO1_YEAST Saccharomyces cerevisiae In 71-91 (68-96) 29.0 ± 3.0 11 ± 0 -12.7 -17.8
1.04.58.01. Protein SCO1 homolog, mitochondrial SCO1_HUMAN Homo sapiens In 95-115 (92-121) 22.8 ± 2.0 0 ± 2 -10.1 -26.2
1.04.58.01. Protein SCO2 homolog, mitochondrial SCO2_HUMAN Homo sapiens In 59-79 (55-83) 24.4 ± 2.8 0 ± 0 -7.7 -25.6
1.04.58.01. Uncharacterized protein Q54TT7_DICDI Dictyostelium discoideum In 111-132 (104-140) 31.0 ± 3.2 4 ± 3 -11.0 -15.6
1.04.59.01. Mitochondrial chaperone BCS1 BCS1_HUMAN Homo sapiens Out 15-34 (14-34) 28.0 ± 2.3 6 ± 4 -5.2 -12.3
1.04.59.01. Probable mitochondrial chaperone BCS1-B BCS1B_DICDI Dictyostelium discoideum Out 32-51 (31-51) 32.4 ± 6.4 9 ± 3 -4.0 -17.1
1.04.59.01. Probable mitochondrial chaperone BCS1-A BCS1A_DICDI Dictyostelium discoideum Out 11-32 (6-33) 28.8 ± 3.4 21 ± 6 -5.1 -11.9
1.04.59.01. Mitochondrial chaperone BCS1 BCS1_YEAST Saccharomyces cerevisiae Out 51-70 (50-77) 22.8 ± 0.6 6 ± 1 -5.5 -21.3
1.04.59.03. ATPase family AAA domain-containing protein 3B ATD3B_HUMAN Homo sapiens Out 245-263 (243-269) 22.8 ± 2.0 1 ± 0 -8.9 -24.3
1.04.59.05. ATP-dependent zinc metalloprotease YME1L1 YMEL1_HUMAN Homo sapiens In 292-310 (287-310) 28.6 ± 2.5 1 ± 0 -12.1 -20.4
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 10, mitochondrial FTSHA_ARATH Arabidopsis thaliana Out 135-155 (135-158) 28.8 ± 1.6 9 ± 6 -12.6 -18.8
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 4, mitochondrial FTSH4_ARATH Arabidopsis thaliana In 180-201 (177-204) 29.0 ± 4.8 20 ± 16 -7.5 -16.3
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 3, mitochondrial FTSH3_ARATH Arabidopsis thaliana Out 131-151 (126-151) 28.2 ± 3.6 24 ± 1 -11.5 -20.7
1.04.59.05. Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1 YME1_YEAST Saccharomyces cerevisiae Out 227-248 (224-249) 28.6 ± 1.5 17 ± 0 -3.7 -17.7
1.04.60.01. Assembly factor CBP4 CBP4_YEAST Saccharomyces cerevisiae In 6-30 (4-31) 37.4 ± 4.4 2 ± 5 -7.9 -16.9
1.04.61.01. Inner membrane assembly complex subunit 22 INA22_YEAST Saccharomyces cerevisiae In 40-65 (39-66) 29.4 ± 2.6 34 ± 3 -9.8 -21.6
1.04.61.02. Inner membrane assembly complex subunit 17 INA17_YEAST Saccharomyces cerevisiae In 107-125 (107-133) 27.4 ± 3.7 20 ± 0 -10.8 -16.7
1.04.62.01. Protein FMP25, mitochondrial FMP25_YEAST Saccharomyces cerevisiae In 81-102 (74-102) 31.0 ± 3.2 9 ± 2 -9.3 -16.7
1.04.62.01. Uncharacterized protein Q54YF9_DICDI Dictyostelium discoideum In 4-24 (4-24) 27.6 ± 1.1 17 ± 6 -8.4 -19.3
1.05.52.02. Altered inheritance of mitochondria protein 34, mitochondrial AIM34_YEAST Saccharomyces cerevisiae In 171-188 (171-188) 27.0 ± 1.0 11 ± 2 -2.5 -16.5
1.05.52.04. Altered inheritance of mitochondria protein 39, mitochondrial AIM39_YEAST Saccharomyces cerevisiae Und 158-179 (149-184) 28.8 ± 3.4 5 ± 3 -11.0 -39.8
1.05.52.05. Altered inheritance of mitochondria protein 36, mitochondrial AIM36_YEAST Saccharomyces cerevisiae Und 58-79 (58-86) 26.8 ± 3.2 1 ± 0 -9.4 -32.4
1.05.54.01. Mitochondrial distribution and morphology protein Q54HH1_DICDI Dictyostelium discoideum Und 215-244 (211-247) 29.4 ± 2.6 54 ± 0 -19.0 -26.0
1.05.55.01. LETM1 and EF-hand domain-containing protein 1, mitochondrial LETM1_HUMAN Homo sapiens Out 209-232 (209-232) 31.0 ± 4.8 30 ± 3 -8.2 -28.6
1.05.55.01. LETM1 domain-containing protein LETM2, mitochondrial LETM2_HUMAN Homo sapiens Out 173-201 (173-201) 29.6 ± 3.6 6 ± 4 -12.5 -35.2
1.05.55.01. Mitochondrial distribution and morphology protein 38 MDM38_YEAST Saccharomyces cerevisiae Out 139-162 (139-162) 32.6 ± 5.0 21 ± 12 -7.9 -28.7
1.05.55.01. LETM1 domain-containing protein YLH47, mitochondrial YLH47_YEAST Saccharomyces cerevisiae Out 137-160 (137-160) 31.4 ± 4.6 30 ± 21 -9.6 -28.4
1.05.56.01. MICOS complex subunit MIC10 MOS1_HUMAN Homo sapiens In 17-37 (16-39) 25.6 ± 1.8 0 ± 1 -8.4 -31.3
1.05.56.01. MICOS complex subunit MIC10 MOS1_YEAST Saccharomyces cerevisiae In 41-61 (35-63) 31.2 ± 2.5 2 ± 1 -10.4 -17.5
1.05.56.02. MICOS complex subunit MIC12 AIM5_YEAST Saccharomyces cerevisiae Und 10-27 (6-29) 26.8 ± 1.7 15 ± 4 -2.2 -15.2
1.05.56.03. MICOS complex subunit MIC27 AIM37_YEAST Saccharomyces cerevisiae Und 101-120 (96-123) 27.2 ± 1.8 0 ± 3 -7.3 -24.5
1.05.56.04. MICOS complex subunit MIC60 IMMT_HUMAN Homo sapiens In 46-68 (43-76) 30.4 ± 4.0 11 ± 2 -4.7 -14.2
1.05.56.04. MICOS complex subunit MIC60 FCJ1_YEAST Saccharomyces cerevisiae In 35-57 (26-59) 30.2 ± 1.5 27 ± 3 -7.4 -14.6
1.05.56.04. Uncharacterized protein Q55BP9_DICDI Dictyostelium discoideum In 65-84 (65-86) 29.4 ± 2.4 13 ± 1 -6.3 -19.4
1.06.25.01. MICOS complex subunit MIC26 MIC26_HUMAN Homo sapiens Out 110-130 (110-134) 28.8 ± 2.6 18 ± 15 -5.9 -18.1
1.06.29.01. ATP synthase protein 8 ATP8_HUMAN Homo sapiens Out 7-28 (6-29) 31.4 ± 3.7 2 ± 1 -11.7 -22.9
1.06.29.02. ATP synthase subunit f, mitochondrial ATPK_HUMAN Homo sapiens Und 63-83 (62-90) 31.4 ± 3.1 1 ± 0 -10.0 -14.5
1.06.29.02. ATP synthase subunit f, mitochondrial ATPK_YEAST Saccharomyces cerevisiae Und 71-90 (71-94) 29.0 ± 3.3 0 ± 0 -6.4 -12.7
1.06.29.04. ATP synthase subunit J, mitochondrial ATP18_YEAST Saccharomyces cerevisiae Und 8-27 (8-31) 28.8 ± 2.6 22 ± 4 -4.0 -15.4
1.06.29.05. Probable F-type ATPase subunit K YO020_YEAST Saccharomyces cerevisiae Out 12-33 (12-35) 31.2 ± 3.1 19 ± 0 -10.9 -15.7
1.06.29.05. ATP synthase subunit K, mitochondrial ATP19_YEAST Saccharomyces cerevisiae Out 16-35 (14-38) 28.0 ± 3.4 8 ± 5 -3.0 -15.9
1.06.29.06. ATP synthase protein MI25 MI25_ARATH Arabidopsis thaliana Out 34-51 (34-51) 26.8 ± 1.0 7 ± 6 -4.9 -15.5
1.06.29.06. ATP synthase F(0) complex subunit B1, mitochondrial AT5F1_HUMAN Homo sapiens Und 95-115 (90-116) 31.0 ± 3.9 9 ± 7 -7.8 -16.0
1.06.29.07. 6.8 kDa mitochondrial proteolipid 68MP_HUMAN Homo sapiens Und 21-41 (15-45) 29.0 ± 2.3 1 ± 4 -5.8 -16.7
1.06.29.08. Up-regulated during skeletal muscle growth protein 5 USMG5_HUMAN Homo sapiens Und 28-47 (21-51) 29.4 ± 3.4 4 ± 9 -10.7 -16.6
1.06.29.09. ATP synthase protein 8 ATP8_YEAST Saccharomyces cerevisiae Und 13-41 (12-42) 34.2 ± 4.8 29 ± 0 -19.2 -26.9
1.06.29.10. ATP synthase protein YMF19 YMF19_ARATH Arabidopsis thaliana Out 7-28 (6-30) 28.2 ± 3.3 26 ± 3 -13.4 -22.6
1.06.29.10. ATPase subunit 8 A9CLV7_DICDI Dictyostelium discoideum Out 6-27 (6-29) 30.6 ± 3.2 23 ± 12 -4.6 -20.2
1.06.29.11. ATP synthase subunit g, mitochondrial ATP5L_HUMAN Homo sapiens Und 70-91 (70-96) 29.2 ± 3.9 25 ± 3 -0.7 -16.8
1.06.30.01. Calcium uptake protein 1, mitochondrial MICU1_HUMAN Homo sapiens In 29-51 (26-58) 28.4 ± 1.0 0 ± 0 -11.8 -15.1
1.06.30.01. Calcium uptake protein 3, mitochondrial EFHA2_HUMAN Homo sapiens In 63-85 (54-86) 28.0 ± 1.6 4 ± 2 -5.1 -26.2
1.06.30.01. Calcium uptake protein 2, mitochondrial MICU2_HUMAN Homo sapiens In 32-53 (32-55) 28.8 ± 1.4 2 ± 2 -9.3 -13.5
1.06.30.02. Essential MCU regulator, mitochondrial CV032_HUMAN Homo sapiens Und 66-84 (65-86) 27.0 ± 1.2 0 ± 2 -6.3 -16.3
1.06.31.01. Mitochondrial calcium uniporter regulator 1 MCUR1_HUMAN Homo sapiens In 334-355 (334-358) 28.4 ± 3.3 31 ± 1 -9.4 -17.4
1.06.31.01. Coiled-coil domain-containing protein 90B, mitochondrial CC90B_HUMAN Homo sapiens In 229-250 (228-253) 30.0 ± 1.8 3 ± 0 -13.3 -34.2
1.06.31.01. Putative uncharacterized protein At3g51090 Q94F04_ARATH Arabidopsis thaliana In 276-298 (273-298) 32.2 ± 4.0 8 ± 13 -8.9 -15.4
1.06.31.01. Uncharacterized protein F4IJS1_ARATH Arabidopsis thaliana In 131-156 (131-158) 28.2 ± 5.2 44 ± 0 -15.0 -18.4
1.06.31.01. Expressed protein Q9SIV6_ARATH Arabidopsis thaliana In 207-228 (204-229) 28.0 ± 4.0 25 ± 19 -10.6 -14.2
1.06.31.01. Uncharacterized protein YLR283W, mitochondrial YL283_YEAST Saccharomyces cerevisiae In 258-279 (257-284) 31.2 ± 3.7 1 ± 0 -12.4 -19.3
1.06.31.01. Protein FMP32, mitochondrial FMP32_YEAST Saccharomyces cerevisiae In 184-203 (178-203) 29.4 ± 3.4 4 ± 4 -11.7 -13.6
1.06.32.01. Pentamidine resistance factor, mitochondrial PNT1_YEAST Saccharomyces cerevisiae Und 194-219 (194-219) 30.2 ± 3.4 37 ± 1 -6.3 -31.1
1.07.21.01. Mitochondrial escape protein 2 homolog YME2_DICDI Dictyostelium discoideum In 340-361 (340-366) 31.4 ± 3.6 14 ± 3 -13.0 -19.9
1.07.21.01. Mitochondrial escape protein 2 YME2_YEAST Saccharomyces cerevisiae In 285-306 (283-306) 31.4 ± 2.0 2 ± 1 -11.9 -23.7
1.07.21.01. Uncharacterized protein Q54B92_DICDI Dictyostelium discoideum In 93-111 (92-113) 27.6 ± 1.0 24 ± 17 -5.5 -19.3
1.07.23.01. Putative COX1/OXI3 intron 1 protein AI1M_YEAST Saccharomyces cerevisiae Out 14-32 (14-42) 30.4 ± 0.8 0 ± 1 -15.4 -38.9
1.07.24.01. COX3 mRNA-specific translational activator PET494 PT494_YEAST Saccharomyces cerevisiae Und 74- 95 (74-100) 28.4 ± 2.7 23 ± 3 -8.7 -18.8
1.07.26.01. Pentatricopeptide repeat-containing protein PET309, mitochondrial PT309_YEAST Saccharomyces cerevisiae Out 242-259 (224-259) 23.8 ± 7.0 25 ± 21 -10.5 -14.5
1.09.01.01. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUA1_ARATH Arabidopsis thaliana Out 3-23 (3-26) 30.8 ± 2.4 7 ± 3 -3.8 -9.4
1.09.01.01. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUA1_HUMAN Homo sapiens Out 5-27 (5-29) 26.8 ± 3.9 45 ± 2 -6.5 -19.3
1.09.01.02. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUA3_HUMAN Homo sapiens Out 17-38 (17-48) 31.8 ± 4.2 17 ± 8 -8.1 -20.5
1.09.01.03. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-A NDADA_ARATH Arabidopsis thaliana In 43-64 (42-66) 30.2 ± 3.1 9 ± 7 -9.8 -14.7
1.09.01.03. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13-B NDADB_ARATH Arabidopsis thaliana In 43-64 (42-66) 30.4 ± 3.3 10 ± 7 -9.2 -15.0
1.09.01.03. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUAD_HUMAN Homo sapiens In 30-51 (30-58) 28.6 ± 2.8 27 ± 20 -8.6 -12.6
1.09.01.03. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUAD_DICDI Dictyostelium discoideum In 32-57 (32-61) 28.2 ± 2.0 49 ± 0 -11.1 -18.4
1.09.01.03. Uncharacterized protein E7ENQ6_HUMAN Homo sapiens In 30-51 (30-58) 28.6 ± 2.8 27 ± 20 -8.6 -12.6
1.09.01.04. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUB1_HUMAN Homo sapiens Out 11-28 (11-33) 26.8 ± 1.0 8 ± 7 -0.6 -11.5
1.09.01.05. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-B NDB3B_ARATH Arabidopsis thaliana In 31-51 (25-57) 29.8 ± 4.2 5 ± 8 -5.5 -13.5
1.09.01.05. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUB3_HUMAN Homo sapiens In 67-88 (64-95) 31.4 ± 3.8 5 ± 8 -5.7 -18.8
1.09.01.05. Uncharacterized protein Q54UJ9_DICDI Dictyostelium discoideum In 22-43 (22-47) 32.0 ± 2.4 0 ± 1 -6.4 -20.7
1.09.01.06. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUB4_HUMAN Homo sapiens In 87-108 (87-113) 29.2 ± 2.8 8 ± 8 -8.6 -17.9
1.09.01.07. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUB5_HUMAN Homo sapiens In 67-93 (63-93) 39.0 ± 4.8 2 ± 0 -12.3 -25.7
1.09.01.08. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUB6_HUMAN Homo sapiens In 64-86 (64-88) 30.2 ± 2.9 18 ± 6 -10.3 -16.8
1.09.01.09. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUB8_ARATH Arabidopsis thaliana Und 81-102 (75-103) 31.0 ± 3.9 3 ± 7 -10.4 -15.6
1.09.01.09. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUB8_HUMAN Homo sapiens Und 129-150 (123-150) 29.0 ± 4.0 23 ± 8 -12.7 -19.3
1.09.01.09. Uncharacterized protein E9PQ68_HUMAN Homo sapiens Und 129-150 (123-150) 30.8 ± 0.0 38 ± 0 -12.7 -22.8
1.09.01.09. Uncharacterized protein Q54QH7_DICDI Dictyostelium discoideum Und 72-94 (70-95) 33.2 ± 3.0 4 ± 2 -12.0 -22.0
1.09.01.10. Putative uncharacterized protein At2g42310 Q9SLC8_ARATH Arabidopsis thaliana Und 64-82 (63-84) 27.2 ± 1.5 21 ± 17 -9.1 -14.2
1.09.01.10. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial NDUBB_HUMAN Homo sapiens Und 85-107 (84-109) 31.6 ± 2.9 2 ± 0 -15.2 -23.7
1.09.01.11. NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUC1_HUMAN Homo sapiens Und 41-59 (39-62) 27.0 ± 3.4 7 ± 6 -6.8 -20.3
1.09.01.12. NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUC2_HUMAN Homo sapiens Und 56-74 (51-78) 26.8 ± 2.5 9 ± 16 -5.7 -18.0
1.09.01.12. NADHdehydrogenase[ubiquinone]1subunitC2, isoform 2 NDUCR_HUMAN Homo sapiens Und 56-74 (51-78) 26.8 ± 2.5 9 ± 16 -5.7 -18.0
1.09.01.13. Cytochrome c oxidase subunit NDUFA4 NDUA4_HUMAN Homo sapiens Out 15-33 (15-36) 29.0 ± 3.0 11 ± 1 -6.3 -16.4
1.09.01.13. Uncharacterized transmembrane protein SSD449 Y5202_DICDI Dictyostelium discoideum Out 7-28 (6-32) 32.6 ± 3.2 2 ± 8 -13.9 -20.8
1.09.01.13. Normal mucosa of esophagus-specific gene 1 protein H0YKW5_HUMAN Homo sapiens Out 13-34 (13-46) 27.6 ± 4.0 56 ± 29 -9.2 -15.0
1.09.01.13. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NUA4L_HUMAN Homo sapiens Out 20-43 (20-45) 34.6 ± 2.2 10 ± 2 -9.2 -14.1
1.09.01.13. B12D protein Q9LJ47_ARATH Arabidopsis thaliana Out 9-27 (9-30) 28.6 ± 2.9 13 ± 3 -7.5 -13.8
1.09.01.13. AT3G48140 protein Q42338_ARATH Arabidopsis thaliana Out 10-30 (10-32) 32.0 ± 3.8 4 ± 3 -8.2 -17.7
1.09.01.13. Normal mucosa of esophagus-specific gene 1 protein NMES1_HUMAN Homo sapiens Out 13-34 (13-46) 27.6 ± 4.0 56 ± 29 -9.2 -15.0
1.09.01.15. Uncharacterized protein Q86K57_DICDI Dictyostelium discoideum Und 56-76 (53-79) 30.2 ± 3.5 14 ± 7 -8.3 -18.8
1.09.02.01. Succinate dehydrogenase subunit 3-1, mitochondrial SDH31_ARATH Arabidopsis thaliana Und 187-205 (182-208) 27.6 ± 1.3 5 ± 2 -5.6 -12.8
1.09.02.01. Succinate dehydrogenase subunit 3-2, mitochondrial SDH32_ARATH Arabidopsis thaliana Und 187-205 (182-208) 27.6 ± 1.3 5 ± 2 -5.6 -12.8
1.09.02.01. Succinate dehydrogenase subunit 4, mitochondrial SDH4_ARATH Arabidopsis thaliana Und 129-150 (124-150) 29.8 ± 1.6 27 ± 9 -5.4 -19.0
1.09.03.01. Cytochrome b-c1 complex subunit 10 QCR10_HUMAN Homo sapiens In 17-42 (17-42) 29.4 ± 2.6 33 ± 2 -3.9 -14.2
1.09.03.01. Cytochrome b-c1 complex subunit 10 QCR10_YEAST Saccharomyces cerevisiae In 26-46 (26-46) 31.2 ± 2.9 8 ± 6 -2.6 -15.2
1.09.03.02. Cytochrome b-c1 complex subunit 9 QCR9_YEAST Saccharomyces cerevisiae In 15-35 (15-37) 27.4 ± 3.0 27 ± 2 -7.6 -18.3
1.09.03.02. Probable cytochrome b-c1 complex subunit 9 QCR9_DICDI Dictyostelium discoideum In 21-43 (18-46) 31.8 ± 7.4 28 ± 2 -2.4 -12.2
1.09.03.02. Cytochrome b-c1 complex subunit 9 QCR9_HUMAN Homo sapiens In 18-36 (17-36) 28.2 ± 1.9 5 ± 2 -3.8 -18.5
1.09.03.03. Probable cytochrome b-c1 complex subunit 8 QCR8_DICDI Dictyostelium discoideum In 43-64 (41-68) 28.2 ± 1.4 21 ± 19 -1.7 -12.4
1.09.03.03. Cytochrome b-c1 complex subunit 8 QCR8_YEAST Saccharomyces cerevisiae In 52-70 (48-72) 27.2 ± 1.7 14 ± 14 -2.2 -13.8
1.09.03.03. Cytochrome b-c1 complex subunit 8 QCR8_HUMAN Homo sapiens In 46-68 (44-72) 32.4 ± 3.6 12 ± 1 -3.9 -20.3
1.09.03.04. Ubiquinol-cytochrome-c reductase complex assembly factor 3 UQCC3_HUMAN Homo sapiens In 3-28 (2-29) 29.2 ± 1.8 0 ± 0 -11.2 -26.5
1.09.03.05. Cytochrome b-c1 complex subunit Rieske, mitochondrial UCRI_HUMAN Homo sapiens In 112-130 (106-130) 26.8 ± 2.6 14 ± 7 -4.6 -12.4
1.09.03.05. Putative cytochrome b-c1 complex subunit Rieske-like protein 1 UCRIL_HUMAN Homo sapiens In 118-138 (112-139) 30.8 ± 2.9 7 ± 6 -4.4 -11.9
1.09.03.05. Cytochrome b-c1 complex subunit Rieske, mitochondrial UCRI_YEAST Saccharomyces cerevisiae In 52-71 (48-72) 27.4 ± 1.2 0 ± 3 -3.7 -8.3
1.09.03.05. Cytochrome b-c1 complex subunit Rieske, mitochondrial Q54NW9_DICDI Dictyostelium discoideum In 50-75 (46-78) 25.4 ± 5.4 48 ± 0 -5.8 -12.0
1.09.04.01. Cytochrome c oxidase subunit 8A, mitochondrial COX8A_HUMAN Homo sapiens In 37-59 (37-67) 35.6 ± 2.2 1 ± 1 -13.2 -33.7
1.09.04.01. Cytochrome c oxidase subunit 8C, mitochondrial COX8C_HUMAN Homo sapiens In 41-64 (41-71) 29.4 ± 3.8 39 ± 5 -13.9 -22.5
1.09.04.02. Cytochrome c oxidase subunit 7A-related protein, mitochondrial COX7R_HUMAN Homo sapiens In 85-107 (82-110) 31.6 ± 3.7 15 ± 4 -10.3 -16.4
1.09.04.02. Cytochrome c oxidase subunit 7A1, mitochondrial CX7A1_HUMAN Homo sapiens In 48-69 (48-74) 29.6 ± 3.6 31 ± 0 -1.0 -13.9
1.09.04.02. At4g21108/At4g21108 Q944S8_ARATH Arabidopsis thaliana In 32-54 (32-61) 28.4 ± 3.7 44 ± 0 -8.5 -18.5
1.09.04.02. Cytochrome c oxidase subunit 7A2, mitochondrial CX7A2_HUMAN Homo sapiens In 49-74 (49-76) 30.2 ± 5.4 39 ± 0 -6.4 -16.5
1.09.04.03. Cytochrome c oxidase subunit 7B, mitochondrial COX7B_HUMAN Homo sapiens In 38-57 (35-59) 27.0 ± 1.2 0 ± 2 -5.8 -14.5
1.09.04.03. Cytochrome c oxidase subunit 7B2, mitochondrial CX7B2_HUMAN Homo sapiens In 42-59 (36-61) 27.0 ± 1.6 1 ± 3 -6.9 -14.4
1.09.04.04. Cytochrome c oxidase subunit 7C, mitochondrial COX7C_HUMAN Homo sapiens In 35-58 (31-61) 32.6 ± 3.8 4 ± 3 -2.5 -16.0
1.09.04.04. Cytochrome c oxidase polypeptide VIII, mitochondrial COX8_YEAST Saccharomyces cerevisiae In 51-72 (48-75) 30.8 ± 2.4 3 ± 2 -14.1 -38.7
1.09.04.05. Cytochrome c oxidase subunit 6C COX6C_HUMAN Homo sapiens In 19-39 (14-46) 29.0 ± 2.3 18 ± 4 -12.2 -18.5
1.09.04.06. Cytochrome c oxidase subunit 6A1, mitochondrial CX6A1_HUMAN Homo sapiens In 37-58 (31-62) 28.8 ± 3.6 22 ± 1 -13.8 -23.6
1.09.04.06. Cytochrome c oxidase subunit 6A2, mitochondrial CX6A2_HUMAN Homo sapiens In 27-47 (23-51) 28.4 ± 2.0 15 ± 8 -10.2 -18.8
1.09.04.06. Cytochrome c oxidase polypeptide 6, mitochondrial COX6_DICDI Dictyostelium discoideum In 35-55 (35-59) 30.2 ± 3.4 14 ± 5 -13.0 -16.7
1.09.04.06. Cytochrome c oxidase subunit 6A, mitochondrial COX13_YEAST Saccharomyces cerevisiae In 51-73 (47-80) 31.2 ± 3.8 11 ± 3 -11.8 -20.9
1.09.04.06. Cytochrome c oxidase subunit 6a, mitochondrial COX6A_ARATH Arabidopsis thaliana In 43-63 (38-65) 29.8 ± 3.9 3 ± 4 -10.1 -13.7
1.09.04.07. Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX41_HUMAN Homo sapiens In 100-122 (97-126) 32.6 ± 3.8 1 ± 1 -15.6 -24.5
1.09.04.07. Cytochrome c oxidase subunit 4 isoform 2, mitochondrial COX42_HUMAN Homo sapiens In 101-123 (93-126) 34.8 ± 3.4 2 ± 0 -19.4 -26.0
1.09.04.07. Cytochrome c oxidase polypeptide 5A, mitochondrial COX5A_YEAST Saccharomyces cerevisiae In 94-116 (91-116) 33.0 ± 2.6 11 ± 0 -11.6 -18.4
1.09.04.07. Cytochrome c oxidase polypeptide 5B, mitochondrial COX5B_YEAST Saccharomyces cerevisiae In 89-113 (88-114) 32.0 ± 1.2 1 ± 0 -7.4 -28.6
1.09.04.07. Maintenance of telomere capping protein 3, mitochondrial MTC3_YEAST Saccharomyces cerevisiae In 89-109 (87-113) 28.2 ± 1.4 19 ± 8 -9.9 -16.1
1.09.04.08. Probable cytochrome c oxidase subunit 5C-3 CX5C3_ARATH Arabidopsis thaliana In 16-36 (14-44) 31.0 ± 3.1 6 ± 4 -6.6 -16.5
1.09.04.08. Putative cytochrome c oxidase subunit 5C-4 CX5C4_ARATH Arabidopsis thaliana In 19-40 (15-44) 29.6 ± 3.9 21 ± 17 -5.6 -13.5
1.09.04.08. Probable cytochrome c oxidase subunit 5C-1 CX5C1_ARATH Arabidopsis thaliana In 15-37 (14-44) 34.0 ± 3.2 11 ± 9 -7.8 -17.4
1.09.04.08. Cytochrome c oxidase subunit 5C-2 CX5C2_ARATH Arabidopsis thaliana In 16-36 (14-44) 29.4 ± 3.0 0 ± 8 -6.8 -16.2
1.09.04.09. Cytochrome c oxidase subunit 7 COX7_YEAST Saccharomyces cerevisiae In 27-48 (27-48) 28.6 ± 3.5 34 ± 2 -8.4 -20.2
1.09.04.10. Cytochrome c oxidase subunit 7c COXS_DICDI Dictyostelium discoideum In 12-34 (12-42) 33.0 ± 3.3 0 ± 0 -9.0 -14.9
1.09.04.10. Cytochrome c oxidase subunit 7A COX9_YEAST Saccharomyces cerevisiae In 11-33 (8-42) 33.0 ± 2.3 7 ± 6 -10.2 -16.5
1.09.04.10. Cytochrome c oxidase subunit 7e COXE_DICDI Dictyostelium discoideum In 13-34 (6-38) 30.2 ± 3.7 7 ± 11 -4.5 -12.8
1.09.05.01. Cytochrome c1, heme protein, mitochondrial CY1_HUMAN Homo sapiens Out 288-307 (281-309) 28.2 ± 2.8 14 ± 3 -14.9 -24.1
1.09.05.01. Cytochrome c1, heme protein, mitochondrial CY1_DICDI Dictyostelium discoideum Out 240-259 (234-261) 29.8 ± 3.7 5 ± 3 -11.0 -21.4
1.09.05.01. Cytochrome c1, heme protein, mitochondrial CY1_YEAST Saccharomyces cerevisiae Out 267-290 (263-290) 30.6 ± 2.2 26 ± 0 -8.8 -15.9
1.09.06.01. Dihydroorotate dehydrogenase (quinone), mitochondrial PYRD_ARATH Arabidopsis thaliana In 51-69 (46-72) 28.6 ± 2.2 0 ± 6 -5.0 -11.0
1.09.06.01. Dihydroorotate dehydrogenase (quinone), mitochondrial PYRD_HUMAN Homo sapiens In 8-29 (2-31) 31.2 ± 3.5 8 ± 7 -6.2 -13.9
1.09.07.01. D-lactate dehydrogenase [cytochrome] 1, mitochondrial DLD1_YEAST Saccharomyces cerevisiae Und 43-64 (38-69) 30.4 ± 3.1 7 ± 3 -7.2 -12.6
1.09.07.02. FAD-dependent oxidoreductase domain-containing protein 1 FXRD1_HUMAN Homo sapiens Out 61-83 (61-89) 27.2 ± 2.6 2 ± 1 -4.8 -22.1
1.09.07.03. Apoptosis-inducing factor 3 AIFM3_HUMAN Homo sapiens Und 191-213 (187-216) 31.0 ± 4.0 1 ± 1 -4.2 -13.2
1.09.39.02. Cytochrome c-type biogenesis CcmH-like mitochondrial protein CCMH_ARATH Arabidopsis thaliana Out 82-108 (82-111) 30.6 ± 7.6 39 ± 9 -11.4 -13.6
1.10.30.04. Methyltransferase OMS1, mitochondrial OMS1_YEAST Saccharomyces cerevisiae In 105-125 (105-131) 29.4 ± 3.4 7 ± 14 -11.7 -18.6
1.10.31.02. Tafazzin TAZ_HUMAN Homo sapiens In 14-35 (14-39) 30.2 ± 3.5 29 ± 2 -7.7 -14.2
1.11.06.02. Serine protease HTRA2, mitochondrial HTRA2_HUMAN Homo sapiens In 103-124 (99-126) 27.2 ± 1.2 0 ± 4 -9.4 -24.9
1.11.08.01. Mitochondrial inner membrane protease subunit 2 IMP2L_HUMAN Homo sapiens In 12-34 (7-38) 29.4 ± 3.4 31 ± 16 -4.8 -21.2
1.11.08.01. Mitochondrial inner membrane protease subunit 2 IMP2_YEAST Saccharomyces cerevisiae Out 135-152 (135-152) 26.8 ± 0.8 11 ± 13 -3.9 -12.4
1.11.08.01. Uncharacterized protein Q54RP1_DICDI Dictyostelium discoideum Out 280-302 (278-305) 29.0 ± 2.2 36 ± 0 -11.5 -24.4
1.11.14.01. Protein MRG3-like MGR3L_YEAST Saccharomyces cerevisiae In 51-72 (50-76) 26.4 ± 2.6 1 ± 1 -7.3 -26.3
1.11.14.01. Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3 MGR3_YEAST Saccharomyces cerevisiae In 79- 97 (77-100) 27.2 ± 1.9 1 ± 1 -6.2 -15.8
1.11.23.01. N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D, mitochondrial FMP30_YEAST Saccharomyces cerevisiae Und 54-75 (46-81) 26.8 ± 1.5 26 ± 4 -8.3 -15.9
1.12.06.01. Phosphatidylserine decarboxylase proenzyme 1, mitochondrial PSD1_YEAST Saccharomyces cerevisiae Und 76-97 (70-98) 24.4 ± 2.4 0 ± 0 -12.0 -32.6
1.12.06.01. Phosphatidylserine decarboxylase proenzyme 1, mitochondrial PSD1_ARATH Arabidopsis thaliana Und 71- 90 (69-104) 27.2 ± 1.8 2 ± 1 -11.8 -33.1
1.15.01.23. Small integral membrane protein 20 CD052_HUMAN Homo sapiens Und 105-127 (99-128) 30.8 ± 3.2 4 ± 0 -10.6 -38.1
1.15.01.26. Uncharacterized protein YKL065W-A YK065_YEAST Saccharomyces cerevisiae Und 33-54 (30-58) 31.2 ± 3.8 2 ± 2 -5.9 -19.7
1.15.01.26. UPF0495 protein YPR010C-A YP010_YEAST Saccharomyces cerevisiae Und 24-45 (24-47) 32.8 ± 3.3 8 ± 5 -9.0 -15.5
1.15.01.26. Uncharacterized protein YDR119W-A YD19A_YEAST Saccharomyces cerevisiae Und 41-60 (38-64) 26.0 ± 4.8 1 ± 3 -5.0 -23.0
1.15.03.26. Protein FAM173A F173A_HUMAN Homo sapiens In 20-43 (20-43) 29.4 ± 6.0 31 ± 2 -9.4 -9.2
1.15.04.01. Stationary phase gene 1 protein SPG1_YEAST Saccharomyces cerevisiae Und 20-38 (18-40) 28.0 ± 1.3 0 ± 0 -6.4 -16.2
1.15.04.02. Uncharacterized protein YPL168W YP168_YEAST Saccharomyces cerevisiae Und 400-420 (397-424) 24.8 ± 1.4 8 ± 4 -11.2 -28.5
1.15.04.02. Uncharacterized protein YGL230C YGY0_YEAST Saccharomyces cerevisiae Und 84-108 (74-111) 26.6 ± 8.4 46 ± 0 -19.8 -24.4
1.15.04.02. Uncharacterized protein YBL059W YBF9_YEAST Saccharomyces cerevisiae Und 119-143 (114-148) 33.2 ± 2.8 0 ± 0 -8.1 -34.6
1.15.43.01. Genetic interactor of prohibitin 7, mitochondrial GEP7_YEAST Saccharomyces cerevisiae Und 248-266 (248-271) 28.2 ± 2.2 29 ± 17 -7.9 -16.4