Lysosomal membrane (24 proteins)

Family Protein Name Protein ID Species Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.01.04.02. Macrosialin CD68_HUMAN Homo sapiens Out 317-344 (315-347) 40.0 ± 3.2 6 ± 5 -27.0 -33.5
1.01.04.02. Lysosome-associated membrane glycoprotein 5 LAMP5_HUMAN Homo sapiens Out 236-258 (236-260) 33.2 ± 1.6 1 ± 2 -19.2 -25.6
1.01.04.02. Lysosome-associated membrane glycoprotein 1 LAMP1_HUMAN Homo sapiens Out 382-405 (379-410) 34.4 ± 4.2 0 ± 4 -19.8 -22.9
1.01.04.02. Lysosome-associated membrane glycoprotein 2 LAMP2_HUMAN Homo sapiens Out 375-398 (372-401) 32.4 ± 2.0 0 ± 3 -21.1 -43.6
1.01.04.02. Lysosome-associated membrane glycoprotein 3 LAMP3_HUMAN Homo sapiens Out 379-404 (378-407) 32.4 ± 1.6 0 ± 0 -15.5 -34.1
1.01.25.01. Sialomucin core protein 24 MUC24_HUMAN Homo sapiens Out 162-187 (162-191) 34.8 ± 1.0 0 ± 0 -17.0 -42.6
1.02.01.03. HLA class II histocompatibility antigen, DO alpha chain DOA_HUMAN Homo sapiens Out 215-243 (215-248) 40.4 ± 2.0 0 ± 0 -21.0 -54.4
1.02.52.01. Transmembrane protein 9 TMEM9_HUMAN Homo sapiens Out 83-111 (80-112) 31.2 ± 5.2 43 ± 0 -19.0 -24.0
1.02.52.01. Transmembrane protein 9B TMM9B_HUMAN Homo sapiens Out 99-124 (94-125) 35.6 ± 4.6 11 ± 10 -17.4 -26.9
1.04.02.01. GTPase IMAP family member 5 GIMA5_HUMAN Homo sapiens In 283-306 (283-306) 33.6 ± 3.4 18 ± 16 -26.5 -29.6
1.04.35.01. Cation-dependent mannose-6-phosphate receptor MPRD_HUMAN Homo sapiens Out 185-210 (181-218) 37.2 ± 2.0 3 ± 2 -16.0 -36.3
1.04.35.02. Cation-independent mannose-6-phosphate receptor MPRI_HUMAN Homo sapiens Out 2303-2330 (2299-2333) 34.0 ± 2.2 2 ± 0 -21.8 -38.4
1.04.35.02. Mannose 6-phosphate receptor-like protein 1 MRL1_YEAST Saccharomyces cerevisiae Out 236-258 (236-265) 26.4 ± 1.8 0 ± 1 -14.7 -32.6
1.05.15.01. Transmembrane protein 106B T106B_HUMAN Homo sapiens In 95-117 (91-117) 35.2 ± 2.0 0 ± 5 -16.2 -49.2
1.05.27.01. Ceroid-lipofuscinosis neuronal protein 5 CLN5_HUMAN Homo sapiens In 24-44 (17-45) 29.8 ± 2.1 1 ± 1 -5.9 -13.6
1.05.27.01. Cln5-like protein 1 CLN5A_DICDI Dictyostelium discoideum Out 308-332 (308-335) 34.8 ± 5.2 21 ± 3 -14.2 -20.8
1.05.27.01. Cln5-like protein 3 CLN5C_DICDI Dictyostelium discoideum Out 366-390 (365-398) 32.4 ± 5.6 31 ± 1 -19.1 -27.3
1.07.16.01. Glycosylated lysosomal membrane protein NCUG1_HUMAN Homo sapiens Out 368-394 (368-399) 31.2 ± 5.4 46 ± 3 -16.2 -24.6
1.11.07.01. Proprotein convertase subtilisin/kexin type 4 PCSK4_HUMAN Homo sapiens Out 706-729 (706-729) 30.8 ± 3.2 26 ± 20 -8.7 -16.9
1.11.25.02. Lysosomal acid phosphatase PPAL_HUMAN Homo sapiens Out 378-406 (378-408) 40.8 ± 1.6 0 ± 0 -26.3 -29.7
1.11.42.01. Sperm acrosome membrane-associated protein 1 SACA1_HUMAN Homo sapiens Out 217-253 (217-254) 34.0 ± 2.8 56 ± 4 -33.7 -37.2
1.11.42.01. Sperm acrosome membrane-associated protein 3 SACA3_HUMAN Homo sapiens In 64-83 (64-87) 27.6 ± 1.3 1 ± 2 -8.0 -17.5
1.14.01.02. E3 ubiquitin-protein ligase RNF167 RN167_HUMAN Homo sapiens Out 172-196 (172-201) 34.8 ± 3.8 9 ± 8 -16.2 -23.6
1.14.04.01. Osteopetrosis-associated transmembrane protein 1 OSTM1_HUMAN Homo sapiens Out 283-305 (282-312) 33.8 ± 1.9 4 ± 2 -16.8 -26.4