1.04.59. AAA-type ATPase superfamily - PF00004 (Pfam) (53 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.04.59.01. Mitochondrial chaperone BCS1 BCS1_HUMAN Homo sapiens Mito. inner memb. Out 15-34 (14-34) 28.0 ± 2.3 6 ± 4 -5.2 -12.3
1.04.59.01. P-loop containing nucleoside triphosphate hydrolases superfamily protein F4JGS0_ARATH Arabidopsis thaliana Membrane Out 66-88 (63-90) 31.6 ± 2.8 6 ± 3 -11.8 -17.5
1.04.59.01. AAA-type ATPase family protein Q8RY66_ARATH Arabidopsis thaliana Membrane Out 4-23 (3-24) 25.6 ± 2.6 1 ± 0 -6.9 -19.8
1.04.59.01. AAA-type ATPase family protein Q9LJJ7_ARATH Arabidopsis thaliana Membrane Out 7-26 (6-26) 27.8 ± 2.1 14 ± 4 -6.8 -14.4
1.04.59.01. 26S proteasome regulatory particle chain RPT6-like protein Q9T090_ARATH Arabidopsis thaliana Membrane Out 6-31 (5-32) 36.4 ± 4.6 8 ± 9 -10.9 -16.3
1.04.59.01. P-loop containing nucleoside triphosphate hydrolases superfamily protein F4JKF8_ARATH Arabidopsis thaliana Membrane Out 2-22 (2-27) 24.0 ± 4.6 0 ± 1 -4.0 -19.1
1.04.59.01. P-loop containing nucleoside triphosphate hydrolases superfamily protein F4JPK8_ARATH Arabidopsis thaliana Membrane Out 4-25 (3-26) 31.2 ± 5.0 4 ± 3 -9.6 -23.3
1.04.59.01. AAA-type ATPase family protein Q9FKM3_ARATH Arabidopsis thaliana Membrane Out 4-22 (3-24) 25.2 ± 1.4 0 ± 0 -7.4 -20.1
1.04.59.01. AAA ATPase domain-containing protein Q54L95_DICDI Dictyostelium discoideum Membrane Out 70-93 (68-96) 32.8 ± 4.8 1 ± 13 -17.3 -22.5
1.04.59.01. Probable mitochondrial chaperone BCS1-B BCS1B_DICDI Dictyostelium discoideum Mito. inner memb. Out 32-51 (31-51) 32.4 ± 6.4 9 ± 3 -4.0 -17.1
1.04.59.01. Probable mitochondrial chaperone BCS1-A BCS1A_DICDI Dictyostelium discoideum Mito. inner memb. Out 11-32 (6-33) 28.8 ± 3.4 21 ± 6 -5.1 -11.9
1.04.59.01. Mitochondrial chaperone BCS1 BCS1_YEAST Saccharomyces cerevisiae Mito. inner memb. Out 51-70 (50-77) 22.8 ± 0.6 6 ± 1 -5.5 -21.3
1.04.59.02. ATPase family AAA domain-containing protein 1 ATAD1_HUMAN Homo sapiens Peroxisome memb. Out 16-38 (13-41) 30.8 ± 3.2 32 ± 1 -7.4 -21.4
1.04.59.02. F9C16.7 Q9LP11_ARATH Arabidopsis thaliana Membrane Out 11-32 (9-35) 29.6 ± 1.4 5 ± 0 -6.0 -32.3
1.04.59.02. P-loop containing nucleoside triphosphate hydrolases superfamily protein F4IJ77_ARATH Arabidopsis thaliana Membrane Out 3-27 (3-28) 36.4 ± 5.0 6 ± 5 -16.8 -27.4
1.04.59.02. AT3g50930/F18B3_210 Q8VZG2_ARATH Arabidopsis thaliana Membrane Out 56-78 (50-78) 30.8 ± 4.0 16 ± 6 -10.8 -15.3
1.04.59.02. P-loop containing nucleoside triphosphate hydrolases superfamily protein F4IQG2_ARATH Arabidopsis thaliana Membrane Out 12-32 (12-33) 29.8 ± 2.8 18 ± 8 -8.0 -14.2
1.04.59.02. At3g50940 Q147F9_ARATH Arabidopsis thaliana Membrane Out 9-31 (4-31) 32.6 ± 3.1 1 ± 0 -13.0 -16.1
1.04.59.02. 26S proteasome regulatory particle chain RPT6-like protein Q9FJC9_ARATH Arabidopsis thaliana Membrane Out 12-34 (12-35) 27.6 ± 1.0 0 ± 2 -8.5 -36.7
1.04.59.02. AAA-type ATPase family protein F4KF14_ARATH Arabidopsis thaliana Membrane Out 238-263 (235-267) 23.2 ± 0.2 57 ± 1 -10.8 -22.0
1.04.59.02. AAA-ATPase 1 Q9FLD5_ARATH Arabidopsis thaliana Membrane Out 8-26 (6-26) 26.4 ± 1.4 0 ± 0 -5.2 -28.2
1.04.59.02. AAA-type ATPase family protein Q9LH84_ARATH Arabidopsis thaliana Membrane Out 7-27 (2-29) 30.0 ± 4.0 17 ± 3 -9.2 -17.5
1.04.59.02. AAA-type ATPase family protein Q2V3R7_ARATH Arabidopsis thaliana Membrane Out 6-25 (3-25) 29.4 ± 4.0 3 ± 7 -8.3 -16.7
1.04.59.02. Cell division control protein 48 homolog B CD48B_ARATH Arabidopsis thaliana Membrane Out 569-590 (566-592) 30.6 ± 2.8 12 ± 8 -7.2 -13.9
1.04.59.02. AAA ATPase domain-containing protein Q1ZXK7_DICDI Dictyostelium discoideum Membrane Out 4-26 (2-36) 27.6 ± 2.0 30 ± 2 -10.8 -19.2
1.04.59.02. Protein MSP1 MSP1_YEAST Saccharomyces cerevisiae Mito. outer memb. Out 5-26 (5-28) 31.6 ± 2.2 5 ± 17 -7.4 -16.6
1.04.59.03. ATPase family AAA domain-containing protein 3A ATD3A_HUMAN Homo sapiens Mito. outer memb. Out 292-312 (291-313) 29.2 ± 2.4 6 ± 5 -8.7 -15.3
1.04.59.03. ATPase family AAA domain-containing protein 3B ATD3B_HUMAN Homo sapiens Mito. inner memb. Out 245-263 (243-269) 22.8 ± 2.0 1 ± 0 -8.9 -24.3
1.04.59.03. ATPase family AAA domain-containing protein 3C ATD3C_HUMAN Homo sapiens Membrane Out 69-88 (67-93) 25.6 ± 3.2 3 ± 2 -8.9 -16.9
1.04.59.03. P-loop containing nucleoside triphosphate hydrolases superfamily protein Q0WVF7_ARATH Arabidopsis thaliana Membrane Out 281-300 (280-305) 29.8 ± 2.8 1 ± 1 -7.7 -14.3
1.04.59.03. AAA-type ATPase family protein Q8RXI0_ARATH Arabidopsis thaliana Membrane Out 291-310 (290-315) 25.2 ± 2.0 4 ± 3 -8.6 -24.0
1.04.59.03. AAA-type ATPase-like protein Q9ZPW5_ARATH Arabidopsis thaliana Membrane Out 277-297 (276-302) 24.4 ± 2.4 0 ± 0 -7.7 -24.1
1.04.59.03. AAA-type ATPase family protein F4JQE9_ARATH Arabidopsis thaliana Membrane Out 276-295 (274-300) 29.0 ± 2.7 4 ± 3 -6.5 -13.1
1.04.59.04. Spastin SPAST_HUMAN Homo sapiens Endosome memb. Out 55-80 (54-90) 28.0 ± 2.8 44 ± 0 -13.2 -20.5
1.04.59.04. Spastin SPAST_DICDI Dictyostelium discoideum Endosome memb. Out 47-69 (43-74) 31.2 ± 5.4 28 ± 20 -19.7 -29.9
1.04.59.05. ATP-dependent zinc metalloprotease YME1L1 YMEL1_HUMAN Homo sapiens Mito. inner memb. In 292-310 (287-310) 28.6 ± 2.5 1 ± 0 -12.1 -20.4
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 10, mitochondrial FTSHA_ARATH Arabidopsis thaliana Mito. inner memb. Out 135-155 (135-158) 28.8 ± 1.6 9 ± 6 -12.6 -18.8
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 11, chloroplastic/mitochondrial FTSHB_ARATH Arabidopsis thaliana Thyl. memb. In 301-326 (298-329) 31.2 ± 4.8 36 ± 4 -17.4 -22.6
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 8, chloroplastic FTSH8_ARATH Arabidopsis thaliana Thyl. memb. Out 161-183 (161-187) 29.6 ± 3.9 32 ± 4 -9.2 -19.6
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 6, chloroplastic FTSH6_ARATH Arabidopsis thaliana Thyl. memb. Out 169-190 (164-195) 29.0 ± 2.7 21 ± 3 -11.3 -22.7
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 5, chloroplastic FTSH5_ARATH Arabidopsis thaliana Thyl. memb. Out 192-213 (192-214) 29.4 ± 2.9 24 ± 4 -8.1 -20.7
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 4, mitochondrial FTSH4_ARATH Arabidopsis thaliana Mito. inner memb. In 180-201 (177-204) 29.0 ± 4.8 20 ± 16 -7.5 -16.3
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 2, chloroplastic FTSH2_ARATH Arabidopsis thaliana Thyl. memb. Out 169-190 (163-193) 31.2 ± 3.6 15 ± 7 -9.6 -19.0
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 3, mitochondrial FTSH3_ARATH Arabidopsis thaliana Mito. inner memb. Out 131-151 (126-151) 28.2 ± 3.6 24 ± 1 -11.5 -20.7
1.04.59.05. ATP-dependent zinc metalloprotease FTSH 1, chloroplastic FTSH1_ARATH Arabidopsis thaliana Thyl. memb. Out 203-227 (202-228) 34.0 ± 3.8 15 ± 8 -12.4 -24.4
1.04.59.05. Peptidase M41 with AAA domain Q55GV8_DICDI Dictyostelium discoideum Membrane Und 112-133 (111-136) 30.6 ± 3.9 19 ± 6 -13.1 -25.2
1.04.59.05. Peptidase M41 with AAA domain Q54BW7_DICDI Dictyostelium discoideum Membrane Und 247-269 (247-277) 30.4 ± 3.4 23 ± 3 -10.2 -25.4
1.04.59.05. Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1 YME1_YEAST Saccharomyces cerevisiae Mito. inner memb. Out 227-248 (224-249) 28.6 ± 1.5 17 ± 0 -3.7 -17.7
1.04.59.05. ATP-dependent zinc metalloprotease FtsH FTSH_ECOLI Escherichia coli Gram-neg. inner Out 98-120 (94-124) 30.4 ± 3.2 25 ± 4 -18.8 -22.7
1.04.59.06. P-loop containing nucleoside triphosphate hydrolase family protein F4JKP9_ARATH Arabidopsis thaliana Membrane Und 23-45 (22-48) 33.4 ± 2.7 9 ± 5 -16.6 -23.6
1.04.59.06. At2g15730 Q6NM29_ARATH Arabidopsis thaliana Membrane Und 23-44 (22-48) 30.8 ± 3.0 14 ± 12 -13.7 -21.3
1.04.59.06. P-loop containing nucleoside triphosphate hydrolase superfamily protein F4JS75_ARATH Arabidopsis thaliana Membrane Und 356-377 (356-378) 30.4 ± 2.0 0 ± 0 -18.5 -40.3
1.04.59.07. Putative general secretion pathway protein A GSPA_ECOLI Escherichia coli Gram-neg. inner In 239-261 (232-264) 29.6 ± 4.2 32 ± 1 -12.2 -17.6