1.14.06. AMP-binding enzymes - PF00501 (Pfam) (8 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.14.06.01. Long-chain-fatty-acid--CoA ligase 1 ACSL1_HUMAN Homo sapiens Mito. outer memb. Out 25-46 (24-47) 32.0 ± 2.6 12 ± 10 -11.0 -20.4
1.14.06.01. Long-chain-fatty-acid--CoA ligase 3 ACSL3_HUMAN Homo sapiens ER memb. Out 20-45 (20-48) 36.0 ± 2.2 25 ± 1 -11.9 -22.4
1.14.06.01. Long-chain-fatty-acid--CoA ligase 4 ACSL4_HUMAN Homo sapiens Golgi memb. Out 7-36 (7-38) 30.8 ± 0.8 52 ± 0 -17.1 -25.3
1.14.06.01. Long-chain-fatty-acid--CoA ligase 5 ACSL5_HUMAN Homo sapiens Mito. outer memb. Out 2-32 (2-34) 29.8 ± 1.6 60 ± 0 -13.5 -28.4
1.14.06.01. Long-chain-fatty-acid--CoA ligase 6 ACSL6_HUMAN Homo sapiens ER memb. Out 27-46 (25-46) 29.6 ± 3.5 3 ± 2 -14.5 -17.8
1.14.06.01. Long chain acyl-CoA synthetase 8 LACS8_ARATH Arabidopsis thaliana Membrane Und 20-44 (20-50) 30.4 ± 2.4 29 ± 0 -10.3 -17.2
1.14.06.02. Long-chain fatty acid transport protein 1 S27A1_HUMAN Homo sapiens Plasma memb. Out 8-33 (8-39) 30.8 ± 3.4 3 ± 1 -9.2 -25.5
1.14.06.03. Long-chain fatty acid transport protein 6 S27A6_HUMAN Homo sapiens Plasma memb. Und 27-47 (26-50) 29.0 ± 3.2 13 ± 1 -4.0 -21.0