1.11.06. Peptidase clan PA (CL0124) (22 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.11.06.01. Enteropeptidase ENTK_HUMAN Homo sapiens Plasma memb. In 17-41 (16-47) 37.2 ± 4.0 5 ± 5 -28.2 -28.9
1.11.06.01. Serine protease hepsin HEPS_HUMAN Homo sapiens Plasma memb. In 18-44 (14-46) 36.0 ± 2.8 27 ± 0 -17.6 -22.9
1.11.06.01. Prostasin PRSS8_HUMAN Homo sapiens Plasma memb. Out 316-340 (316-342) 34.4 ± 1.6 18 ± 16 -3.0 -23.3
1.11.06.01. Transmembrane protease serine 11A TM11A_HUMAN Homo sapiens Plasma memb. In 17-42 (17-48) 39.6 ± 3.2 2 ± 1 -25.2 -42.2
1.11.06.01. Transmembrane protease serine 11B TM11B_HUMAN Homo sapiens Plasma memb. In 12-43 (12-43) 38.8 ± 1.6 2 ± 2 -23.9 -59.7
1.11.06.01. Transmembrane protease serine 11D TM11D_HUMAN Homo sapiens Plasma memb. In 16-41 (16-43) 39.6 ± 1.8 0 ± 0 -27.8 -49.8
1.11.06.01. Transmembrane protease serine 11E TM11E_HUMAN Homo sapiens Plasma memb. In 16-41 (16-49) 34.4 ± 3.4 34 ± 3 -22.5 -24.8
1.11.06.01. Transmembrane protease serine 11F TM11F_HUMAN Homo sapiens Plasma memb. In 30-52 (25-57) 34.0 ± 1.6 3 ± 1 -21.8 -44.0
1.11.06.01. Transmembrane protease serine 2 TMPS2_HUMAN Homo sapiens Plasma memb. In 83-109 (79-112) 34.4 ± 4.2 29 ± 1 -18.5 -26.5
1.11.06.01. Transmembrane protease serine 3 TMPS3_HUMAN Homo sapiens ER memb. In 48-69 (48-74) 30.8 ± 4.8 37 ± 21 -22.3 -23.7
1.11.06.01. Transmembrane protease serine 4 TMPS4_HUMAN Homo sapiens Plasma memb. In 25-57 (25-59) 33.6 ± 3.6 48 ± 1 -21.8 -35.8
1.11.06.01. Transmembrane protease serine 5 TMPS5_HUMAN Homo sapiens Plasma memb. In 48-72 (43-72) 35.6 ± 2.4 22 ± 19 -8.7 -15.4
1.11.06.01. Transmembrane protease serine 6 TMPS6_HUMAN Homo sapiens Plasma memb. In 49-76 (41-78) 36.4 ± 4.2 19 ± 10 -24.2 -31.4
1.11.06.01. Transmembrane protease serine 7 TMPS7_HUMAN Homo sapiens Plasma memb. In 59-87 (59-91) 34.0 ± 3.8 32 ± 1 -27.7 -32.8
1.11.06.01. Transmembrane protease serine 9 TMPS9_HUMAN Homo sapiens Plasma memb. In 28-50 (23-59) 36.8 ± 1.8 3 ± 0 -17.8 -43.3
1.11.06.01. Transmembrane protease serine 12 TMPSC_HUMAN Homo sapiens Plasma memb. Out 330-348 (328-348) 28.8 ± 2.7 2 ± 1 -7.2 -17.0
1.11.06.01. Transmembrane protease serine 13 TMPSD_HUMAN Homo sapiens Plasma memb. In 160-186 (160-187) 34.4 ± 4.0 27 ± 3 -22.7 -27.7
1.11.06.01. Tryptase gamma TRYG1_HUMAN Homo sapiens Plasma memb. Out 281-309 (281-309) 34.0 ± 4.8 28 ± 0 -13.8 -27.8
1.11.06.02. Serine protease HTRA2, mitochondrial HTRA2_HUMAN Homo sapiens Mito. inner memb. In 103-124 (99-126) 32.6 ± 3.2 0 ± 0 -9.4 -16.5
1.11.06.02. Serine endoprotease DegS DEGS_ECOLI Escherichia coli Gram-neg. inner In 5-27 (3-29) 30.8 ± 5.2 29 ± 5 -10.5 -20.4
1.11.06.03. Suppressor of tumorigenicity 14 protein ST14_HUMAN Homo sapiens Plasma memb. In 54-79 (54-85) 39.2 ± 2.0 0 ± 1 -25.2 -52.1
1.11.06.04. Atrial natriuretic peptide-converting enzyme CORIN_HUMAN Homo sapiens Plasma memb. In 42-70 (39-74) 40.8 ± 4.6 6 ± 4 -24.2 -36.0