1.11.01. Peptidase clan AA (CL0129) (6 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.11.01.01. Beta-secretase 1 BACE1_HUMAN Homo sapiens Plasma memb. Out 450-479 (450-487) 34.4 ± 0.0 44 ± 0 -20.8 -27.3
1.11.01.01. Beta-secretase 2 BACE2_HUMAN Homo sapiens Plasma memb. Out 465-494 (465-499) 34.0 ± 3.8 45 ± 4 -23.8 -29.3
1.11.01.01. Aspartyl protease family protein Q9SN13_ARATH Arabidopsis thaliana Membrane Out 583-605 (583-611) 30.8 ± 4.2 30 ± 9 -18.4 -16.7
1.11.01.01. Aspartyl protease family protein F4K4L3_ARATH Arabidopsis thaliana Membrane Out 575-600 (570-607) 30.8 ± 3.8 35 ± 4 -15.4 -18.5
1.11.01.01. Uncharacterized protein Q54WT3_DICDI Dictyostelium discoideum Membrane Out 682-708 (680-710) 40.0 ± 3.2 1 ± 1 -22.4 -26.1
1.11.01.02. Retroviral-like aspartic protease 1 APRV1_HUMAN Homo sapiens ER memb. In 56-77 (55-77) 24.8 ± 1.2 0 ± 2 -10.5 -22.8