1.11.39. Tim barrel glycosyl hydrolase superfamily (CL0058) (17 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.11.39.01. Klotho KLOT_HUMAN Homo sapiens Plasma memb. Out 979-1004 (976-1006) 36.0 ± 1.2 0 ± 0 -23.3 -41.8
1.11.39.01. Beta-klotho KLOTB_HUMAN Homo sapiens Plasma memb. Out 996-1020 (996-1023) 34.4 ± 2.0 24 ± 4 -16.0 -23.1
1.11.39.01. Lactase-like protein LCTL_HUMAN Homo sapiens ER memb. Out 536-563 (535-566) 39.6 ± 4.6 5 ± 5 -15.8 -25.2
1.11.39.01. Lactase-phlorizin hydrolase LPH_HUMAN Homo sapiens Plasma memb. Out 1882-1904 (1877-1909) 33.6 ± 2.2 0 ± 0 -19.5 -36.1
1.11.39.01. Beta-glucosidase 26, peroxisomal BGL26_ARATH Arabidopsis thaliana Plasma memb. Out 534-558 (534-558) 34.4 ± 3.6 22 ± 10 -8.3 -16.3
1.11.39.02. Uncharacterized family 31 glucosidase KIAA1161 K1161_HUMAN Homo sapiens Nucleus memb. In 57-79 (56-83) 30.0 ± 1.8 8 ± 5 -19.1 -37.0
1.11.39.02. Maltase-glucoamylase, intestinal MGA_HUMAN Homo sapiens Plasma memb. In 11-36 (11-40) 34.0 ± 3.2 35 ± 0 -28.3 -35.0
1.11.39.02. Probable maltase-glucoamylase-like protein LOC93432 MGAL2_HUMAN Homo sapiens Membrane In 7-32 (7-35) 36.0 ± 1.6 0 ± 1 -20.4 -39.7
1.11.39.02. Sucrase-isomaltase, intestinal SUIS_HUMAN Homo sapiens Plasma memb. In 8-35 (8-35) 36.0 ± 5.0 29 ± 1 -28.9 -34.6
1.11.39.03. Hyaluronidase-4 HYAL4_HUMAN Homo sapiens Plasma memb. In 9-33 (6-33) 34.4 ± 1.8 9 ± 5 -8.7 -15.9
1.11.39.04. Glycoprotein endo-alpha-1,2-mannosidase MANEA_HUMAN Homo sapiens Golgi memb. In 7-29 (2-30) 31.6 ± 3.4 27 ± 21 -21.4 -27.0
1.11.39.04. Glycoprotein endo-alpha-1,2-mannosidase-like protein MANEL_HUMAN Homo sapiens Golgi memb. In 8-29 (2-31) 29.2 ± 1.8 1 ± 0 -18.6 -41.0
1.11.39.05. Uncharacterized protein MJ1477 Y1477_METJA Methanococcus jannaschii Archaebacterial memb. Und 12-33 (9-33) 32.8 ± 3.4 11 ± 10 -16.6 -20.8
1.11.39.06. Beta-galactosidase 9 BGAL9_ARATH Arabidopsis thaliana Membrane Und 9-28 (9-33) 27.8 ± 3.3 10 ± 5 -11.0 -17.7
1.11.39.07. Galactose-binding domain-containing protein Q54MD5_DICDI Dictyostelium discoideum Membrane Und 530-549 (527-549) 29.4 ± 2.3 2 ± 1 -12.7 -17.3
1.11.39.07. Uncharacterized protein Q54MB3_DICDI Dictyostelium discoideum Membrane Und 522-542 (518-542) 26.8 ± 1.8 0 ± 4 -12.4 -34.1
1.11.39.08. Glycosyl hydrolase family protein Q9M159_ARATH Arabidopsis thaliana ER memb. Und 34-56 (30-56) 34.4 ± 1.4 5 ± 5 -21.4 -26.1