1.11.20. AB hydrolase (50 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.11.20.01. Arylacetamide deacetylase AAAD_HUMAN Homo sapiens ER memb. In 3-21 (3-21) 27.2 ± 1.6 10 ± 7 -7.6 -15.1
1.11.20.01. Neutral cholesterol ester hydrolase 1 NCEH1_HUMAN Homo sapiens ER memb. In 3-21 (2-21) 27.0 ± 1.2 11 ± 1 -10.2 -16.3
1.11.20.01. Arylacetamide deacetylase-like 4 ADCL4_HUMAN Homo sapiens ER memb. In 2-24 (2-25) 31.6 ± 1.2 32 ± 5 -19.3 -28.7
1.11.20.01. Probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL1 ICML1_ARATH Arabidopsis thaliana ER memb. In 149-175 (147-176) 36.0 ± 1.6 1 ± 1 -8.1 -34.2
1.11.20.01. Probable isoprenylcysteine alpha-carbonyl methylesterase ICMEL2 ICML2_ARATH Arabidopsis thaliana ER memb. In 93-119 (91-126) 39.2 ± 1.8 4 ± 3 -13.6 -36.3
1.11.20.01. Isoprenylcysteine alpha-carbonyl methylesterase ICME ICME_ARATH Arabidopsis thaliana ER memb. In 98-124 (96-130) 33.6 ± 3.8 29 ± 0 -12.5 -24.3
1.11.20.02. Monoacylglycerol lipase ABHD6 ABHD6_HUMAN Homo sapiens Vesicle memb. In 5-34 (5-38) 31.6 ± 1.0 45 ± 0 -17.4 -29.2
1.11.20.02. Epoxide hydrolase 4 EPHX4_HUMAN Homo sapiens Vesicle memb. In 19-40 (15-45) 36.8 ± 8.8 7 ± 3 -4.9 -16.5
1.11.20.02. Mesoderm-specific transcript homolog protein MEST_HUMAN Homo sapiens ER memb. In 10-30 (5-31) 27.8 ± 1.7 10 ± 2 -8.8 -19.6
1.11.20.02. AT5G53050 protein B9DG68_ARATH Arabidopsis thaliana Membrane Out 357-378 (357-381) 29.4 ± 2.0 31 ± 25 -17.6 -22.7
1.11.20.03. Abhydrolase domain-containing protein 1 ABHD1_HUMAN Homo sapiens Vesicle memb. In 13-34 (12-35) 28.0 ± 2.0 7 ± 5 -13.0 -33.2
1.11.20.03. Abhydrolase domain-containing protein 2 ABHD2_HUMAN Homo sapiens Vesicle memb. In 12-33 (11-37) 31.6 ± 3.5 7 ± 17 -6.0 -17.8
1.11.20.03. Abhydrolase domain-containing protein 3 ABHD3_HUMAN Homo sapiens Vesicle memb. In 27-49 (20-55) 33.6 ± 2.0 10 ± 6 -10.6 -36.3
1.11.20.03. Alpha/beta-Hydrolases superfamily protein Q9SF34_ARATH Arabidopsis thaliana Membrane Und 122-143 (122-146) 30.6 ± 3.9 23 ± 2 -17.1 -21.0
1.11.20.03. AT5g02970/F9G14_280 Q9LYY8_ARATH Arabidopsis thaliana Membrane Und 119-140 (119-140) 33.2 ± 3.7 18 ± 1 -18.4 -20.0
1.11.20.03. Uncharacterized protein Q55FN8_DICDI Dictyostelium discoideum Membrane Und 71-92 (70-92) 33.8 ± 2.5 2 ± 0 -14.0 -23.5
1.11.20.04. Alpha/beta-Hydrolases superfamily protein F4HXL0_ARATH Arabidopsis thaliana Membrane Und 688-712 (688-712) 31.6 ± 2.6 29 ± 0 -9.3 -21.8
1.11.20.04. AT3g62590/F26K9_20 Q940L4_ARATH Arabidopsis thaliana Membrane Und 615-633 (611-642) 28.4 ± 4.2 26 ± 1 -8.8 -20.7
1.11.20.04. Putative lipase ATG15 ATG15_YEAST Saccharomyces cerevisiae ER memb. In 14-35 (14-35) 32.0 ± 1.8 16 ± 0 -12.5 -17.8
1.11.20.05. Monoacylglycerol lipase ABHD12 ABD12_HUMAN Homo sapiens Plasma memb. In 69-93 (68-93) 34.4 ± 4.2 9 ± 11 -8.4 -23.0
1.11.20.05. Alpha/beta hydrolase domain-containing protein 13 ABHDD_HUMAN Homo sapiens Plasma memb. In 32-60 (32-61) 34.4 ± 4.0 42 ± 2 -20.5 -28.5
1.11.20.05. Bem46-family protein WAV2 Q8RXP6_ARATH Arabidopsis thaliana Membrane Und 4-29 (4-30) 32.0 ± 2.6 29 ± 0 -12.4 -20.4
1.11.20.05. Alpha/beta-Hydrolases superfamily protein Q9C915_ARATH Arabidopsis thaliana Membrane Und 3-21 (3-25) 30.6 ± 2.6 1 ± 0 -10.8 -18.0
1.11.20.05. Uncharacterized protein Q54H73_DICDI Dictyostelium discoideum Membrane Und 8-29 (2-32) 31.2 ± 3.3 2 ± 1 -12.3 -14.1
1.11.20.05. Tentative alpha/beta-hydrolase YN60_YEAST Saccharomyces cerevisiae Plasma memb. In 4-26 (3-31) 34.0 ± 3.0 1 ± 14 -11.7 -19.1
1.11.20.05. Uncharacterized protein YfhR YFHR_ECOLI Escherichia coli Gram-neg. inner Und 9-29 (8-30) 29.6 ± 2.5 15 ± 3 -8.9 -24.1
1.11.20.06. Alpha/beta hydrolase domain-containing protein 14A ABHEA_HUMAN Homo sapiens Vesicle memb. In 32-52 (29-52) 27.2 ± 1.2 0 ± 0 -13.6 -34.0
1.11.20.07. Transmembrane protein 53 TMM53_HUMAN Homo sapiens Membrane Und 167-200 (167-204) 28.8 ± 2.8 59 ± 5 -27.4 -35.6
1.11.20.07. Uncharacterized protein Q54YR8_DICDI Dictyostelium discoideum Membrane Und 156-178 (154-178) 31.2 ± 1.8 8 ± 6 -20.8 -28.3
1.11.20.07. Uncharacterized protein Q54N85_DICDI Dictyostelium discoideum Membrane Und 194-216 (192-218) 31.6 ± 3.0 2 ± 1 -9.3 -21.3
1.11.20.08. Phospholipid:diacylglycerol acyltransferase 1 PDAT1_ARATH Arabidopsis thaliana ER memb. In 54-73 (52-75) 29.2 ± 4.6 8 ± 1 -9.9 -18.3
1.11.20.08. Putative phospholipid:diacylglycerol acyltransferase 2 PDAT2_ARATH Arabidopsis thaliana ER memb. In 45-66 (44-66) 26.8 ± 3.2 10 ± 0 -9.4 -16.8
1.11.20.08. Lecithin-cholesterol acyltransferase-like 1 LCAT1_ARATH Arabidopsis thaliana Vacuole memb. In 7-25 (4-26) 27.0 ± 1.6 10 ± 8 -11.6 -14.5
1.11.20.08. Phospholipid--sterol O-acyltransferase LCAT2_ARATH Arabidopsis thaliana ER memb. In 7-26 (3-29) 28.2 ± 2.8 8 ± 6 -10.2 -20.7
1.11.20.08. Phospholipid:diacylglycerol acyltransferase PDAT_YEAST Saccharomyces cerevisiae ER memb. In 78- 98 (75-100) 26.0 ± 1.0 0 ± 1 -14.1 -36.8
1.11.20.09. Sterol esterase 1 YEH1_YEAST Saccharomyces cerevisiae Lipid droplet In 12-36 (3-39) 30.8 ± 4.6 30 ± 0 -21.8 -25.4
1.11.20.09. Sterol esterase 2 YEH2_YEAST Saccharomyces cerevisiae Plasma memb. In 10-32 (8-34) 34.8 ± 1.9 0 ± 0 -15.3 -16.5
1.11.20.09. Sterol esterase TGL1 TGL1_YEAST Saccharomyces cerevisiae ER memb. Out 9-33 (8-33) 30.0 ± 2.7 27 ± 1 -4.8 -16.8
1.11.20.10. Protein AUXIN RESPONSE 4 AXR4_ARATH Arabidopsis thaliana ER memb. In 44-68 (43-70) 30.8 ± 4.4 29 ± 3 -18.4 -24.8
1.11.20.11. Steryl acetyl hydrolase 1 SAY1_YEAST Saccharomyces cerevisiae ER memb. In 48-73 (41-77) 30.8 ± 2.2 38 ± 1 -16.6 -27.1
1.11.20.12. Protein SERAC1 SRAC1_HUMAN Homo sapiens ER memb. In 33-55 (30-58) 26.0 ± 2.0 1 ± 1 -6.8 -21.2
1.11.20.13. Epoxide hydrolase 1 HYEP_HUMAN Homo sapiens ER memb. In 2-19 (2-25) 31.6 ± 3.6 1 ± 20 -8.5 -18.7
1.11.20.14. Putative lipase YOR059C YO059_YEAST Saccharomyces cerevisiae Lipid droplet Und 268-290 (267-302) 34.4 ± 2.0 2 ± 0 -20.2 -26.0
1.11.20.15. Uncharacterized protein F4J7E1_ARATH Arabidopsis thaliana Membrane Und 162-182 (161-182) 29.6 ± 1.8 9 ± 8 -6.7 -12.7
1.11.20.15. Uncharacterized protein YPR147C YP147_YEAST Saccharomyces cerevisiae Membrane Und 159-178 (156-178) 28.4 ± 3.1 3 ± 12 -5.3 -11.2
1.11.20.16. Uncharacterized protein Q54DJ5_DICDI Dictyostelium discoideum Membrane Und 24-47 (22-51) 34.4 ± 2.4 4 ± 3 -14.0 -26.7
1.11.20.17. Alpha/beta fold hydrolase family protein Q9LYG5_ARATH Arabidopsis thaliana Membrane Und 28-47 (28-47) 29.4 ± 2.6 2 ± 5 -10.9 -19.1
1.11.20.18. Esterase/lipase/thioesterase family protein Q9C914_ARATH Arabidopsis thaliana Membrane Und 17-38 (13-41) 32.2 ± 2.7 9 ± 7 -16.1 -23.7
1.11.20.18. Alpha/beta-hydrolase domain-containing protein Q9STM1_ARATH Arabidopsis thaliana Membrane Und 31-52 (28-53) 26.8 ± 1.2 0 ± 0 -13.0 -33.1
1.11.20.19. Putative uncharacterized protein At3g58800/T20N10_150 Q9LXS2_ARATH Arabidopsis thaliana Membrane Und 16-38 (11-40) 34.4 ± 1.0 2 ± 0 -19.4 -42.7