Superfamily » 1.05.13. Vesicle-associated membrane protein

Type:1. Transmembrane bitopic proteins
Class:1.05. Membrane trafficking and biogenesis
Superfamily:1.05.13. Vesicle-associated membrane protein
Family:
1. 1.05.13.01.
  Vesicle-associated membrane protein IPR016763 (InterPro)
  Motile sperm domain-containing protein 3
  
  Homo sapiens
  (MSPD3_HUMAN)
  
  Uncharacterized protein
  
  Dictyostelium discoideum
  (Q54XS7_DICDI)
  
  Vesicle-associated membrane protein-associated protein A
  
  Homo sapiens
  (VAPA_HUMAN, 1B42, A4, EGFR, ERBB2, ESR1, ITA4, RMD3, VAMP1, VAMP2, VAPB, VCAM1)
  
  Vesicle-associated membrane protein-associated protein B/C
  
  Homo sapiens
  (VAPB_HUMAN, ERBB2, ESR1, OST48, RMD2, SC22B, STX1A, STX1B, STX2, STX4, STX5, UCRI, VAMP1, VAMP2, VAPA)
  
  Vesicle-associated membrane protein-associated protein SCS2
  
  Saccharomyces cerevisiae
  (SCS2_YEAST, ANP1, ATG32, CP51, DPM1, EMC1, EMP24, ERG2, ERP1, FDFT, GOSR1, GPI8, GSF2, MMM1, MTC4, OST1, OSTB, SC6B1, SCS22, SEC66, TMEDA, TOM70, USE1, VOA1, YHO0)
  
  Vesicle-associated membrane protein-associated protein SCS22
  
  Saccharomyces cerevisiae
  (SCS22_YEAST, SCS2)
  
  Vesicle-associated protein 1-1
  
  Arabidopsis thaliana
  (VAP11_ARATH, ATL4, BET11, CYB5A, CYB5E, FIS1A, NPS12, SY132, SYP31, VA722, WIP1)
  
  Vesicle-associated protein 1-2
  
  Arabidopsis thaliana
  (VAP12_ARATH)
  
  Vesicle-associated protein 1-3
  
  Arabidopsis thaliana
  (VAP13_ARATH)
  
  Vesicle-associated protein 2-1
  
  Arabidopsis thaliana
  (VAP21_ARATH, CRK19, CRK2, CRK31, ERL1, FEI2, LRK53, LRK55, MRH1, SRF1, SRF8, WAKLJ, Y2267, Y4361, Y5169)
  
  Vesicle-associated protein 2-2
  
  Arabidopsis thaliana
  (VAP22_ARATH, PAM74)
2. 1.05.13.02.
  Motile sperm domain-containing protein 2
  Motile sperm domain-containing protein 2
  
  Homo sapiens
  (MSPD2_HUMAN)

1.05.13. Vesicle-associated membrane protein (12 proteins)

Family	Protein Name	Protein ID	Species	Localization	Topology	TM Segment (helix)	Hydrophobic Thickness (Å)	Tilt Angle (°)	ΔG_fold (kcal/mol)	ΔG_transf (kcal/mol)
1.05.13.01.	Vesicle-associated membrane protein-associated protein A	VAPA_HUMAN	Homo sapiens	Vesicle memb.	In	227-247 (227-247)	30.4 ± 1.4	2 ± 1	-15.1	-44.9
1.05.13.01.	Vesicle-associated membrane protein-associated protein B/C	VAPB_HUMAN	Homo sapiens	ER memb.	In	219-241 (217-242)	30.0 ± 2.2	0 ± 0	-15.6	-38.8
1.05.13.01.	Motile sperm domain-containing protein 3	MSPD3_HUMAN	Homo sapiens	ER memb.	In	175-197 (172-197)	33.0 ± 2.2	4 ± 3	-16.0	-23.5
1.05.13.01.	Vesicle-associated protein 2-1	VAP21_ARATH	Arabidopsis thaliana	ER memb.	In	196-217 (193-218)	31.6 ± 3.6	3 ± 9	-16.6	-19.9
1.05.13.01.	Vesicle-associated protein 2-2	VAP22_ARATH	Arabidopsis thaliana	ER memb.	In	364-384 (364-385)	29.2 ± 2.7	21 ± 6	-11.7	-17.0
1.05.13.01.	Vesicle-associated protein 1-1	VAP11_ARATH	Arabidopsis thaliana	ER memb.	In	233-254 (233-255)	25.6 ± 1.8	0 ± 0	-14.2	-37.1
1.05.13.01.	Vesicle-associated protein 1-2	VAP12_ARATH	Arabidopsis thaliana	ER memb.	In	216-237 (216-238)	25.6 ± 1.8	0 ± 0	-14.2	-37.1
1.05.13.01.	Vesicle-associated protein 1-3	VAP13_ARATH	Arabidopsis thaliana	ER memb.	In	215-236 (208-238)	29.6 ± 1.4	1 ± 0	-12.4	-37.2
1.05.13.01.	Uncharacterized protein	Q54XS7_DICDI	Dictyostelium discoideum	ER memb.	In	289-309 (289-309)	31.6 ± 3.1	8 ± 5	-15.6	-18.0
1.05.13.01.	Vesicle-associated membrane protein-associated protein SCS22	SCS22_YEAST	Saccharomyces cerevisiae	ER memb.	In	155-175 (153-175)	30.6 ± 1.6	5 ± 2	-12.6	-21.4
1.05.13.01.	Vesicle-associated membrane protein-associated protein SCS2	SCS2_YEAST	Saccharomyces cerevisiae	ER memb.	In	224-243 (222-243)	30.0 ± 2.8	1 ± 7	-18.2	-24.8
1.05.13.02.	Motile sperm domain-containing protein 2	MSPD2_HUMAN	Homo sapiens	ER memb.	In	493-515 (485-517)	31.6 ± 2.2	6 ± 19	-21.3	-24.9