1.04.45. Single TMH-6Cys (CYSTM) superfamily (17 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.04.45.01. Vesicular, overexpressed in cancer, prosurvival protein 1 VOPP1_HUMAN Homo sapiens Vesicle memb. Out 60-82 (56-86) 34.8 ± 2.9 1 ± 2 -16.5 -21.9
1.04.45.02. Protein shisa-9 SHSA9_HUMAN Homo sapiens Plasma memb. Out 150-177 (149-180) 35.2 ± 5.0 32 ± 2 -17.7 -24.5
1.04.45.02. Putative protein shisa-8 SHSA8_HUMAN Homo sapiens Plasma memb. Out 140-161 (135-161) 30.8 ± 3.6 12 ± 4 -12.5 -15.2
1.04.45.02. Protein shisa-2 homolog SHSA2_HUMAN Homo sapiens ER memb. Out 115-136 (115-138) 33.0 ± 2.0 12 ± 0 -15.0 -22.4
1.04.45.02. Protein shisa-3 homolog SHSA3_HUMAN Homo sapiens ER memb. Out 96-122 (96-125) 35.2 ± 1.8 1 ± 0 -17.1 -48.2
1.04.45.02. Protein shisa-4 SHSA4_HUMAN Homo sapiens Plasma memb. Out 83-111 (83-118) 34.0 ± 5.2 45 ± 1 -20.0 -24.1
1.04.45.02. Protein shisa-5 SHSA5_HUMAN Homo sapiens ER memb. Out 109-131 (105-141) 30.8 ± 5.0 29 ± 0 -19.4 -24.6
1.04.45.02. Protein shisa-7 SHSA7_HUMAN Homo sapiens Membrane Out 188-210 (184-213) 32.0 ± 3.4 30 ± 1 -10.7 -13.9
1.04.45.02. Protein shisa-6 homolog SHSA6_HUMAN Homo sapiens Plasma memb. Out 176-200 (168-203) 35.6 ± 3.4 1 ± 1 -17.4 -22.8
1.04.45.03. WW domain binding protein 1-like WBP1L_HUMAN Homo sapiens Membrane Out 40-60 (39-66) 29.6 ± 3.9 8 ± 7 -15.7 -17.1
1.04.45.03. Proline-rich protein 7 PRR7_HUMAN Homo sapiens Plasma memb. Out 9-35 (7-44) 33.6 ± 3.6 37 ± 7 -20.4 -28.2
1.04.45.04. Cysteine and tyrosine-rich protein 1 CYYR1_HUMAN Homo sapiens Membrane Out 63-86 (60-94) 36.0 ± 5.6 1 ± 5 -21.7 -25.1
1.04.45.05. Membrane protein FAM159A F159A_HUMAN Homo sapiens Membrane Out 58-91 (56-93) 31.2 ± 7.4 51 ± 0 -26.5 -28.2
1.04.45.05. Membrane protein FAM159B F159B_HUMAN Homo sapiens Membrane Out 63-92 (59-96) 34.8 ± 3.2 42 ± 0 -26.7 -30.3
1.04.45.06. Transmembrane protein 92 TMM92_HUMAN Homo sapiens Plasma memb. Out 54-76 (53-77) 33.8 ± 1.8 1 ± 1 -16.3 -24.1
1.04.45.07. Uncharacterized protein KIAA1644 K1644_HUMAN Homo sapiens Plasma memb. Out 98-122 (96-123) 34.4 ± 2.0 18 ± 14 -20.5 -24.7
1.04.45.08. Cadmium tolerance 1 F4IEL4_ARATH Arabidopsis thaliana Membrane Out 20-40 (11-43) 30.0 ± 3.6 1 ± 0 -4.3 -10.5