1.11.15. Nicastrin - PF05450 (Pfam) (5 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.11.15.01. Nicastrin NICA_HUMAN Homo sapiens Plasma memb. Out 667-690 (667-694) 34.4 ± 1.8 9 ± 6 -16.9 -23.8
1.11.15.01. Nicastrin NICA_ARATH Arabidopsis thaliana Plasma memb. Out 644-673 (642-674) 34.4 ± 2.6 35 ± 8 -13.6 -19.4
1.11.15.01. Nicastrin NICA_DICDI Dictyostelium discoideum Plasma memb. Out 626-652 (623-656) 35.2 ± 4.4 23 ± 11 -12.8 -27.9
1.11.15.02. Nicalin NCLN_HUMAN Homo sapiens ER memb. Out 521-542 (521-544) 31.8 ± 2.0 22 ± 11 -11.7 -17.9
1.11.15.02. Nicalin Q9M292_ARATH Arabidopsis thaliana ER memb. Out 515-544 (513-545) 42.8 ± 0.4 0 ± 0 -21.0 -49.6