1.03.05. Cadherin - PF00028 (Pfam) (110 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.03.05.01. Cadherin-10 CAD10_HUMAN Homo sapiens Plasma memb. Out 612-635 (611-641) 32.0 ± 1.8 0 ± 0 -31.3 -54.5
1.03.05.01. Cadherin-11 CAD11_HUMAN Homo sapiens Plasma memb. Out 614-640 (613-644) 34.8 ± 2.2 0 ± 0 -30.0 -61.2
1.03.05.01. Cadherin-12 CAD12_HUMAN Homo sapiens Plasma memb. Out 615-637 (614-641) 29.2 ± 1.4 0 ± 0 -28.4 -53.8
1.03.05.01. Cadherin-15 CAD15_HUMAN Homo sapiens Plasma memb. Out 602-629 (602-634) 37.6 ± 4.0 18 ± 16 -27.3 -31.6
1.03.05.01. Cadherin-16 CAD16_HUMAN Homo sapiens Plasma memb. Out 780-808 (780-814) 38.4 ± 0.8 0 ± 0 -25.5 -61.4
1.03.05.01. Cadherin-17 CAD17_HUMAN Homo sapiens Plasma memb. Out 786-808 (783-814) 34.4 ± 1.2 2 ± 2 -26.2 -61.1
1.03.05.01. Cadherin-18 CAD18_HUMAN Homo sapiens Plasma memb. Out 611-636 (608-640) 38.8 ± 3.4 3 ± 2 -32.2 -62.1
1.03.05.01. Cadherin-19 CAD19_HUMAN Homo sapiens Plasma memb. Out 596-620 (596-623) 31.2 ± 1.8 1 ± 2 -24.0 -57.1
1.03.05.01. Cadherin-20 CAD20_HUMAN Homo sapiens Plasma memb. Out 620-642 (619-646) 31.2 ± 2.2 3 ± 2 -27.1 -47.7
1.03.05.01. Cadherin-22 CAD22_HUMAN Homo sapiens Plasma memb. Out 624-648 (624-650) 30.4 ± 1.4 0 ± 0 -27.8 -52.5
1.03.05.01. Cadherin-23 CAD23_HUMAN Homo sapiens Plasma memb. Out 3062-3090 (3059-3094) 42.8 ± 0.4 0 ± 0 -34.7 -57.1
1.03.05.01. Cadherin-24 CAD24_HUMAN Homo sapiens Plasma memb. Out 637-662 (634-666) 39.2 ± 1.6 1 ± 1 -24.5 -52.5
1.03.05.01. Cadherin-like protein 26 CAD26_HUMAN Homo sapiens Plasma memb. Out 613-642 (608-643) 40.8 ± 5.8 14 ± 7 -21.0 -30.3
1.03.05.01. Cadherin-1 CADH1_HUMAN Homo sapiens Plasma memb. Out 706-731 (706-735) 32.8 ± 1.4 0 ± 0 -28.6 -53.4
1.03.05.01. Cadherin-2 CADH2_HUMAN Homo sapiens Plasma memb. Out 722-747 (722-755) 32.4 ± 1.4 0 ± 0 -33.5 -59.4
1.03.05.01. Cadherin-3 CADH3_HUMAN Homo sapiens Plasma memb. Out 651-679 (648-681) 33.2 ± 2.6 0 ± 3 -27.4 -53.0
1.03.05.01. Cadherin-4 CADH4_HUMAN Homo sapiens Plasma memb. Out 732-757 (732-763) 31.6 ± 1.2 0 ± 0 -31.9 -57.6
1.03.05.01. Cadherin-5 CADH5_HUMAN Homo sapiens Plasma memb. Out 597-621 (596-625) 30.8 ± 1.8 0 ± 0 -25.7 -47.7
1.03.05.01. Cadherin-6 CADH6_HUMAN Homo sapiens Plasma memb. Out 614-636 (613-643) 32.8 ± 1.8 0 ± 0 -27.7 -53.1
1.03.05.01. Cadherin-7 CADH7_HUMAN Homo sapiens Plasma memb. Out 605-630 (602-636) 38.0 ± 3.4 0 ± 0 -29.6 -55.5
1.03.05.01. Cadherin-8 CADH8_HUMAN Homo sapiens Plasma memb. Out 616-648 (616-648) 41.2 ± 2.0 0 ± 0 -31.6 -67.3
1.03.05.01. Cadherin-9 CADH9_HUMAN Homo sapiens Plasma memb. Out 611-638 (609-643) 32.4 ± 2.0 0 ± 0 -31.6 -54.2
1.03.05.02. Calsyntenin-1 CSTN1_HUMAN Homo sapiens Plasma memb. Out 859-882 (857-887) 32.8 ± 2.0 4 ± 2 -21.5 -36.9
1.03.05.02. Calsyntenin-2 CSTN2_HUMAN Homo sapiens Plasma memb. Out 828-856 (828-858) 34.0 ± 3.4 45 ± 5 -21.2 -29.6
1.03.05.02. Calsyntenin-3 CSTN3_HUMAN Homo sapiens Plasma memb. Out 843-871 (843-875) 34.0 ± 3.6 42 ± 0 -21.8 -32.2
1.03.05.03. Desmocollin-1 DSC1_HUMAN Homo sapiens Plasma memb. Out 691-714 (691-718) 31.6 ± 1.2 0 ± 0 -19.8 -45.6
1.03.05.03. Desmocollin-2 DSC2_HUMAN Homo sapiens Plasma memb. Out 694-716 (694-719) 31.6 ± 1.2 0 ± 0 -23.0 -39.5
1.03.05.03. Desmocollin-3 DSC3_HUMAN Homo sapiens Plasma memb. Out 690-718 (690-721) 42.0 ± 1.6 0 ± 0 -24.2 -58.0
1.03.05.04. Desmoglein-1 DSG1_HUMAN Homo sapiens Plasma memb. Out 548-570 (548-570) 34.2 ± 1.2 3 ± 3 -12.9 -23.2
1.03.05.04. Desmoglein-2 DSG2_HUMAN Homo sapiens Plasma memb. Out 612-637 (612-642) 34.8 ± 4.6 1 ± 1 -27.3 -47.6
1.03.05.04. Desmoglein-3 DSG3_HUMAN Homo sapiens Plasma memb. Out 618-640 (618-641) 34.0 ± 1.1 3 ± 2 -21.3 -25.8
1.03.05.04. Desmoglein-4 DSG4_HUMAN Homo sapiens Plasma memb. Out 630-654 (630-658) 34.8 ± 4.0 16 ± 13 -22.1 -27.3
1.03.05.05. Protocadherin Fat 1 FAT1_HUMAN Homo sapiens Plasma memb. Out 4181-4208 (4181-4212) 34.0 ± 3.8 31 ± 4 -22.7 -30.3
1.03.05.05. Protocadherin Fat 2 FAT2_HUMAN Homo sapiens Plasma memb. Out 4048-4070 (4046-4073) 32.8 ± 2.2 1 ± 1 -20.7 -40.1
1.03.05.05. Protocadherin Fat 3 FAT3_HUMAN Homo sapiens Plasma memb. Out 4154-4176 (4152-4178) 34.8 ± 0.8 1 ± 6 -28.1 -31.2
1.03.05.05. Protocadherin Fat 4 FAT4_HUMAN Homo sapiens Plasma memb. Out 4500-4525 (4499-4534) 34.4 ± 1.6 0 ± 0 -14.5 -46.4
1.03.05.06. Cadherin-related family member 3 CDHR3_HUMAN Homo sapiens Plasma memb. Out 710-739 (707-740) 31.2 ± 0.6 0 ± 1 -20.7 -43.9
1.03.05.06. Cadherin-related family member 4 CDHR4_HUMAN Homo sapiens Plasma memb. Out 686-711 (686-715) 34.4 ± 2.0 0 ± 4 -16.8 -48.7
1.03.05.06. Cadherin-related family member 5 CDHR5_HUMAN Homo sapiens Plasma memb. Out 662-691 (659-694) 36.8 ± 4.2 40 ± 2 -21.6 -27.6
1.03.05.06. Protocadherin-11 X-linked PC11X_HUMAN Homo sapiens Plasma memb. Out 810-834 (808-839) 34.0 ± 2.2 2 ± 1 -22.7 -50.9
1.03.05.06. Protocadherin-11 Y-linked PC11Y_HUMAN Homo sapiens Plasma memb. Out 842-866 (840-871) 34.0 ± 2.2 2 ± 1 -22.7 -50.9
1.03.05.06. Protocadherin-10 PCD10_HUMAN Homo sapiens Plasma memb. Out 714-738 (714-744) 34.4 ± 3.2 21 ± 6 -25.8 -27.3
1.03.05.06. Protocadherin-12 PCD12_HUMAN Homo sapiens Plasma memb. Out 715-743 (714-744) 32.4 ± 1.8 6 ± 5 -25.5 -45.7
1.03.05.06. Protocadherin-15 PCD15_HUMAN Homo sapiens Plasma memb. Out 1373-1400 (1372-1407) 40.4 ± 3.8 1 ± 0 -22.8 -30.6
1.03.05.06. Protocadherin-16 PCD16_HUMAN Homo sapiens Plasma memb. Out 2935-2960 (2935-2966) 38.8 ± 1.2 0 ± 0 -24.2 -52.1
1.03.05.06. Protocadherin-17 PCD17_HUMAN Homo sapiens Plasma memb. Out 706-730 (706-733) 34.4 ± 3.0 24 ± 9 -20.3 -24.5
1.03.05.06. Protocadherin-18 PCD18_HUMAN Homo sapiens Plasma memb. Out 700-722 (698-728) 34.2 ± 1.1 0 ± 0 -25.4 -26.4
1.03.05.06. Protocadherin-19 PCD19_HUMAN Homo sapiens Plasma memb. Out 675-702 (674-706) 38.0 ± 1.2 0 ± 1 -25.4 -58.1
1.03.05.06. Protocadherin-20 PCD20_HUMAN Homo sapiens Plasma memb. Out 859-884 (859-888) 34.4 ± 1.8 0 ± 3 -10.8 -35.7
1.03.05.06. Cadherin-related family member 1 CDHR1_HUMAN Homo sapiens Plasma memb. Out 698-723 (698-728) 35.2 ± 1.4 0 ± 0 -19.6 -46.3
1.03.05.06. Protocadherin-23 PCD23_HUMAN Homo sapiens Plasma memb. Out 2539-2564 (2536-2567) 34.8 ± 4.0 21 ± 4 -27.4 -32.6
1.03.05.06. Cadherin-related family member 2 CDHR2_HUMAN Homo sapiens Plasma memb. Out 1148-1177 (1147-1181) 39.6 ± 1.8 2 ± 1 -27.3 -58.1
1.03.05.06. Protocadherin alpha-1 PCDA1_HUMAN Homo sapiens Plasma memb. Out 699-721 (698-724) 32.8 ± 1.8 0 ± 0 -20.8 -39.4
1.03.05.06. Protocadherin alpha-2 PCDA2_HUMAN Homo sapiens Plasma memb. Out 699-721 (698-724) 33.2 ± 2.0 2 ± 1 -20.3 -35.0
1.03.05.06. Protocadherin alpha-3 PCDA3_HUMAN Homo sapiens Plasma memb. Out 698-721 (698-725) 34.4 ± 1.8 1 ± 2 -20.5 -42.4
1.03.05.06. Protocadherin alpha-4 PCDA4_HUMAN Homo sapiens Plasma memb. Out 699-721 (698-724) 32.8 ± 1.8 0 ± 0 -20.8 -39.4
1.03.05.06. Protocadherin alpha-5 PCDA5_HUMAN Homo sapiens Plasma memb. Out 697-720 (697-725) 34.0 ± 1.6 2 ± 2 -21.1 -42.0
1.03.05.06. Protocadherin alpha-6 PCDA6_HUMAN Homo sapiens Plasma memb. Out 699-721 (698-725) 34.8 ± 2.0 0 ± 1 -21.1 -41.2
1.03.05.06. Protocadherin alpha-7 PCDA7_HUMAN Homo sapiens Plasma memb. Out 699-721 (698-725) 34.8 ± 2.0 0 ± 1 -21.1 -41.2
1.03.05.06. Protocadherin alpha-8 PCDA8_HUMAN Homo sapiens Plasma memb. Out 699-721 (698-724) 32.8 ± 1.8 0 ± 0 -20.8 -39.4
1.03.05.06. Protocadherin alpha-9 PCDA9_HUMAN Homo sapiens Plasma memb. Out 699-721 (698-726) 36.4 ± 1.6 3 ± 2 -21.5 -40.3
1.03.05.06. Protocadherin alpha-10 PCDAA_HUMAN Homo sapiens Plasma memb. Out 696-719 (696-724) 34.0 ± 1.6 2 ± 2 -21.6 -42.0
1.03.05.06. Protocadherin alpha-11 PCDAB_HUMAN Homo sapiens Plasma memb. Out 698-723 (697-725) 38.4 ± 0.6 0 ± 0 -21.4 -44.3
1.03.05.06. Protocadherin alpha-12 PCDAC_HUMAN Homo sapiens Plasma memb. Out 699-721 (698-725) 34.8 ± 2.0 0 ± 1 -21.3 -41.2
1.03.05.06. Protocadherin alpha-13 PCDAD_HUMAN Homo sapiens Plasma memb. Out 699-721 (698-725) 34.8 ± 2.0 0 ± 1 -21.1 -41.2
1.03.05.06. Protocadherin beta-1 PCDB1_HUMAN Homo sapiens Plasma memb. Out 688-715 (686-722) 38.0 ± 4.4 18 ± 5 -32.7 -34.5
1.03.05.06. Protocadherin beta-2 PCDB2_HUMAN Homo sapiens Plasma memb. Out 685-717 (682-719) 37.6 ± 2.8 0 ± 0 -22.6 -55.2
1.03.05.06. Protocadherin beta-3 PCDB3_HUMAN Homo sapiens Plasma memb. Out 683-715 (680-717) 37.6 ± 2.8 0 ± 0 -22.6 -55.2
1.03.05.06. Protocadherin beta-4 PCDB4_HUMAN Homo sapiens Plasma memb. Out 684-713 (682-719) 38.4 ± 2.4 0 ± 0 -22.2 -52.8
1.03.05.06. Protocadherin beta-5 PCDB5_HUMAN Homo sapiens Plasma memb. Out 684-713 (682-719) 38.4 ± 2.4 0 ± 0 -22.2 -52.8
1.03.05.06. Protocadherin beta-6 PCDB6_HUMAN Homo sapiens Plasma memb. Out 683-712 (681-718) 38.4 ± 2.4 0 ± 0 -22.2 -52.8
1.03.05.06. Protocadherin beta-7 PCDB7_HUMAN Homo sapiens Plasma memb. Out 684-712 (678-715) 35.6 ± 3.6 0 ± 0 -22.5 -50.2
1.03.05.06. Protocadherin beta-8 PCDB8_HUMAN Homo sapiens Plasma memb. Out 687-715 (683-720) 42.8 ± 0.8 0 ± 0 -24.5 -57.0
1.03.05.06. Protocadherin beta-9 PCDB9_HUMAN Homo sapiens Plasma memb. Out 682-715 (680-717) 42.8 ± 2.2 0 ± 0 -22.7 -57.2
1.03.05.06. Protocadherin beta-10 PCDBA_HUMAN Homo sapiens Plasma memb. Out 684-715 (684-719) 42.8 ± 1.8 0 ± 0 -22.9 -56.8
1.03.05.06. Protocadherin beta-11 PCDBB_HUMAN Homo sapiens Plasma memb. Out 685-714 (683-720) 38.4 ± 2.4 0 ± 0 -22.2 -52.8
1.03.05.06. Protocadherin beta-12 PCDBC_HUMAN Homo sapiens Plasma memb. Out 685-714 (683-720) 38.4 ± 2.4 0 ± 0 -22.2 -52.8
1.03.05.06. Protocadherin beta-13 PCDBD_HUMAN Homo sapiens Plasma memb. Out 683-715 (680-717) 38.0 ± 4.8 40 ± 7 -22.8 -28.1
1.03.05.06. Protocadherin beta-14 PCDBE_HUMAN Homo sapiens Plasma memb. Out 685-714 (683-720) 38.4 ± 2.4 0 ± 0 -22.2 -52.8
1.03.05.06. Protocadherin beta-15 PCDBF_HUMAN Homo sapiens Plasma memb. Out 686-715 (683-720) 38.4 ± 2.0 0 ± 0 -22.2 -53.6
1.03.05.06. Protocadherin beta-16 PCDBG_HUMAN Homo sapiens Plasma memb. Out 686-715 (680-717) 42.4 ± 0.8 1 ± 0 -22.1 -56.5
1.03.05.06. Putative protocadherin beta-18 PCDBI_HUMAN Homo sapiens Plasma memb. Out 630-662 (627-664) 38.4 ± 5.8 36 ± 3 -22.4 -27.9
1.03.05.06. Protocadherin alpha-C1 PCDC1_HUMAN Homo sapiens Plasma memb. Out 682-707 (679-710) 37.2 ± 1.6 0 ± 1 -22.0 -41.6
1.03.05.06. Protocadherin alpha-C2 PCDC2_HUMAN Homo sapiens Plasma memb. Out 703-733 (701-737) 35.2 ± 3.8 44 ± 3 -29.0 -30.9
1.03.05.06. Protocadherin gamma-A1 PCDG1_HUMAN Homo sapiens Plasma memb. Out 689-714 (686-717) 35.2 ± 2.0 0 ± 1 -25.8 -47.6
1.03.05.06. Protocadherin gamma-A2 PCDG2_HUMAN Homo sapiens Plasma memb. Out 689-716 (686-717) 38.0 ± 1.4 0 ± 3 -26.2 -52.7
1.03.05.06. Protocadherin gamma-A3 PCDG3_HUMAN Homo sapiens Plasma memb. Out 689-716 (686-717) 35.6 ± 1.4 1 ± 1 -28.3 -46.9
1.03.05.06. Protocadherin gamma-A4 PCDG4_HUMAN Homo sapiens Plasma memb. Out 689-716 (684-717) 40.4 ± 1.4 0 ± 0 -26.1 -49.5
1.03.05.06. Protocadherin gamma-A5 PCDG5_HUMAN Homo sapiens Plasma memb. Out 687-716 (684-717) 42.8 ± 1.6 2 ± 1 -30.3 -53.8
1.03.05.06. Protocadherin gamma-A6 PCDG6_HUMAN Homo sapiens Plasma memb. Out 689-716 (686-717) 35.6 ± 1.4 1 ± 1 -27.7 -46.9
1.03.05.06. Protocadherin gamma-A7 PCDG7_HUMAN Homo sapiens Plasma memb. Out 689-716 (687-717) 40.8 ± 2.2 1 ± 1 -27.9 -50.8
1.03.05.06. Protocadherin gamma-A8 PCDG8_HUMAN Homo sapiens Plasma memb. Out 689-714 (686-717) 37.2 ± 2.0 0 ± 0 -25.9 -48.5
1.03.05.06. Protocadherin gamma-A9 PCDG9_HUMAN Homo sapiens Plasma memb. Out 685-716 (685-717) 34.4 ± 1.4 0 ± 0 -25.4 -48.2
1.03.05.06. Protocadherin gamma-A10 PCDGA_HUMAN Homo sapiens Plasma memb. Out 689-720 (688-721) 40.8 ± 4.0 28 ± 3 -25.6 -31.3
1.03.05.06. Protocadherin gamma-A11 PCDGB_HUMAN Homo sapiens Plasma memb. Out 693-718 (688-724) 38.4 ± 2.6 4 ± 0 -29.4 -53.7
1.03.05.06. Protocadherin gamma-A12 PCDGC_HUMAN Homo sapiens Plasma memb. Out 689-717 (684-717) 40.4 ± 4.4 19 ± 7 -28.2 -32.6
1.03.05.06. Protocadherin gamma-B1 PCDGD_HUMAN Homo sapiens Plasma memb. Out 684-712 (681-715) 40.8 ± 4.4 16 ± 9 -31.0 -35.1
1.03.05.06. Protocadherin gamma-B2 PCDGE_HUMAN Homo sapiens Plasma memb. Out 689-714 (684-720) 41.2 ± 2.6 1 ± 0 -30.9 -59.6
1.03.05.06. Protocadherin gamma-B3 PCDGF_HUMAN Homo sapiens Plasma memb. Out 688-715 (685-720) 39.6 ± 4.4 13 ± 10 -30.9 -34.6
1.03.05.06. Protocadherin gamma-B4 PCDGG_HUMAN Homo sapiens Plasma memb. Out 681-710 (681-717) 38.4 ± 2.0 0 ± 3 -31.0 -54.5
1.03.05.06. Protocadherin gamma-B5 PCDGH_HUMAN Homo sapiens Plasma memb. Out 684-712 (681-715) 37.2 ± 4.4 24 ± 10 -31.1 -33.7
1.03.05.06. Protocadherin gamma-B6 PCDGI_HUMAN Homo sapiens Plasma memb. Out 684-716 (683-719) 36.8 ± 6.4 38 ± 6 -31.3 -34.0
1.03.05.06. Protocadherin gamma-B7 PCDGJ_HUMAN Homo sapiens Plasma memb. Out 688-713 (683-716) 38.8 ± 1.6 0 ± 0 -31.0 -51.5
1.03.05.06. Protocadherin gamma-C3 PCDGK_HUMAN Homo sapiens Plasma memb. Out 690-718 (684-718) 35.6 ± 3.6 29 ± 0 -22.4 -33.2
1.03.05.06. Protocadherin gamma-C4 PCDGL_HUMAN Homo sapiens Plasma memb. Out 685-713 (684-719) 38.8 ± 0.8 2 ± 0 -16.4 -39.0
1.03.05.06. Protocadherin gamma-C5 PCDGM_HUMAN Homo sapiens Plasma memb. Out 690-712 (689-715) 33.8 ± 1.8 3 ± 2 -20.5 -22.7
1.03.05.06. Protocadherin-1 PCDH1_HUMAN Homo sapiens Plasma memb. Out 851-877 (843-880) 35.2 ± 1.6 1 ± 1 -24.9 -51.7
1.03.05.06. Protocadherin-7 PCDH7_HUMAN Homo sapiens Plasma memb. Out 878-900 (871-907) 36.0 ± 1.8 1 ± 0 -28.8 -57.1
1.03.05.06. Protocadherin-8 PCDH8_HUMAN Homo sapiens Plasma memb. Out 748-774 (747-780) 40.0 ± 4.8 0 ± 0 -24.0 -25.6
1.03.05.06. Protocadherin-9 PCDH9_HUMAN Homo sapiens Plasma memb. Out 812-836 (810-842) 36.4 ± 2.0 0 ± 0 -28.5 -55.0