1.01.07.01. Toll-like receptors - IPR017241 (InterPro) (10 proteins)

Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
Toll-like receptor 1 TLR1_HUMAN Homo sapiens Plasma memb. Out 575-603 (574-604) 33.6 ± 1.6 0 ± 0 -21.6 -38.1
Toll-like receptor 10 TLR10_HUMAN Homo sapiens Plasma memb. Out 571-603 (571-603) 39.2 ± 1.4 2 ± 1 -25.3 -42.7
Toll-like receptor 2 TLR2_HUMAN Homo sapiens Plasma memb. Out 588-612 (582-613) 32.8 ± 1.8 0 ± 2 -15.4 -33.7
Toll-like receptor 3 TLR3_HUMAN Homo sapiens Endosome memb. Out 701-726 (701-729) 34.4 ± 1.0 0 ± 0 -22.0 -55.9
Toll-like receptor 4 TLR4_HUMAN Homo sapiens Plasma memb. Out 633-659 (631-662) 37.2 ± 2.2 0 ± 2 -16.5 -35.4
Toll-like receptor 5 TLR5_HUMAN Homo sapiens Plasma memb. Out 635-663 (631-664) 36.8 ± 5.4 1 ± 0 -24.7 -40.4
Toll-like receptor 6 TLR6_HUMAN Homo sapiens Plasma memb. Out 580-611 (579-611) 42.0 ± 2.8 0 ± 2 -21.1 -44.8
Toll-like receptor 7 TLR7_HUMAN Homo sapiens Endosome memb. Out 837-862 (837-865) 38.8 ± 1.2 0 ± 1 -14.7 -40.2
Toll-like receptor 8 TLR8_HUMAN Homo sapiens Endosome memb. Out 825-853 (825-854) 41.2 ± 1.2 1 ± 0 -26.8 -51.6
Toll-like receptor 9 TLR9_HUMAN Homo sapiens Endosome memb. Out 816-838 (816-838) 31.6 ± 3.4 3 ± 0 -10.8 -33.4