1.11.07.01. Peptidase S8, subtilisin-related - IPR015500 (InterPro) (8 proteins)

Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
Furin FURIN_HUMAN Homo sapiens Golgi memb. Out 714-736 (711-737) 33.6 ± 3.2 2 ± 1 -19.3 -39.0
Kexin KEX2_YEAST Saccharomyces cerevisiae Golgi memb. Out 673-701 (673-703) 30.8 ± 4.0 46 ± 11 -24.5 -28.4
Membrane-bound transcription factor site-1 protease MBTP1_HUMAN Homo sapiens Golgi memb. Out 1001-1022 (1001-1026) 31.0 ± 3.3 13 ± 3 -18.6 -27.0
Proprotein convertase subtilisin/kexin type 4 PCSK4_HUMAN Homo sapiens Lysosome memb. Out 706-729 (706-729) 30.8 ± 3.2 26 ± 20 -8.7 -16.9
Proprotein convertase subtilisin/kexin type 5 PCSK5_HUMAN Homo sapiens Golgi memb. Out 1740-1765 (1737-1768) 35.2 ± 5.6 16 ± 11 -19.8 -25.8
Proprotein convertase subtilisin/kexin type 7 PCSK7_HUMAN Homo sapiens Golgi memb. Out 657-678 (656-685) 30.4 ± 1.6 0 ± 1 -12.1 -34.3
Uncharacterized protein Q55E86_DICDI Dictyostelium discoideum Membrane Out 656-680 (652-684) 30.4 ± 5.6 27 ± 1 -15.7 -21.1
Uncharacterized protein Q55C28_DICDI Dictyostelium discoideum Membrane Out 658-679 (656-679) 31.4 ± 2.3 12 ± 9 -10.4 -25.7